Estradiol Transdermal System Patch
Pricing Report NDC 0781-7104-54

Current NADAC: $12.36109 per EA · Effective Aug 19, 2026 · Est. package price $12.36 (1 EA)
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

The current wholesale acquisition cost for Estradiol Transdermal System (NDC 0781-7104-54) is $12.36109 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Aug 19, 2026.

As a a human prescription drug provided by Sandoz Inc, this medication is distributed in a 4 PATCH in 1 CARTON / 7 d in 1 PATCH (0781-7104-58) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$12.36109
Per EA

Pricing Unit
Per EA Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Aug 19, 2026
Billable Units
1 EA
Estimated Package Price
$12.36
Data Status
As of Sep 09, 2026
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
G - Generic
Package NDC
0781-7104-54
Description
4 PATCH in 1 CARTON / 7 d in 1 PATCH (0781-7104-58)
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Nov 2018, the NADAC wholesale price for (NDC ) has moved within a range of $9.53426 to $15.00868 per EA. Over this 7 years and 9 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$9.5343 - $15.0087
Market Volatility
57.42% Variance
Latest Trend
1.41%

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Aug 19, 2026 $12.36109 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 22, 2026 $12.53743 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 17, 2026 $12.50932 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 20, 2026 $12.44890 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 22, 2026 $11.82302 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 18, 2026 $11.88853 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 18, 2026 $11.80291 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 21, 2026 $12.05726 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 17, 2025 $11.93847 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 19, 2025 $11.93480 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 22, 2025 $12.10732 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 17, 2025 $11.94444 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: September 09, 2026