Myobloc Injection, Solution
NDC Package 10454-710-10
Package Information
Myobloc (rimabotulinumtoxinb) injection is there are different types of botulinum toxin products (toxin A and B) with different uses (eye problems, muscle stiffness/spasms, migraines, cosmetic, overactive bladder). This formulation utilizes a injection, solution delivery system. Marketed by Solstice Neurosciences, Llc, this product is identified by NDC 10454-710 and is authorized under FDA application BLA103846.
Identification & Billing
- RxCUI: 1736640 - rimabotulinumtoxinB 2500 UNT in 0.5 ML Injection
- RxCUI: 1736640 - 0.5 ML rimabotulinumtoxinB 5000 UNT/ML Injection
- RxCUI: 1736640 - rimabotulinumtoxinB 2500 UNT per 0.5 ML Injection
- RxCUI: 1736642 - MYOBLOC 2500 UNT in 0.5 ML Injection
- RxCUI: 1736642 - 0.5 ML rimabotulinumtoxinB 5000 UNT/ML Injection [Myobloc]
Clinical Specifications
Regulatory & Marketing
Hierarchy Structure
- 10454 - Solstice Neurosciences, Llc
- 10454-710 - Myobloc
- 10454-710-10 - 1 VIAL, SINGLE-USE in 1 CARTON / .5 mL in 1 VIAL, SINGLE-USE
- 10454-710 - Myobloc
The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.
* Please review the full disclaimer at the bottom of this page.
Billing & HCPCS Mapping
To facilitate insurance claims and reimbursement, this drug package is mapped to specific HCPCS administrative codes. This crosswalk aligns clinical data with the billing standards used in ASP (Average Sales Price), AWP, and OPPS payment systems. Use the cards below to identify the correct billable units for provider claims.
Note for Medical Coders: These mappings are synthesized from various CMS datasets including OPPS, PrEP, and DAC (Data Analysis and Coding) contractors. Always confirm unit conversions against the current quarter's pricing files before final submission.
* Please review the full disclaimer at the bottom of this page.
Frequently Asked Questions
What is the distribution configuration for this product package?
The code 10454-710-10 identifies a specific commercial package of 1 vial, single-use in 1 carton / .5 ml in 1 vial, single-use of Myobloc, a human prescription drug labeled by Solstice Neurosciences, Llc. This injection, solution is formulated for intramuscular use and contains rimabotulinumtoxinb as the active substance.
Is this product currently listed with the FDA?
Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Solstice Neurosciences, Llc on December 08, 2000. The current certification is valid through December 31, 2026.
What are the primary indications for this medication?
There are different types of botulinum toxin products (toxin A and B) with different uses (eye problems, muscle stiffness/spasms, migraines, cosmetic, overactive bladder). Different brands of this medication deliver different amounts of medication. Your doctor will choose the correct product for you. Botulinum toxin is used to treat certain eye disorders such as crossed eyes (strabismus) and uncontrolled blinking (blepharospasm), to treat muscle stiffness/spasms or movement disorders (such as cervical dystonia, torticollis), and to reduce the cosmetic appearance of wrinkles. It is also used to prevent headaches in people with very frequent migraines. Botulinum toxin relaxes muscle by blocking the release of a chemical called acetylcholine. Botulinum toxin is also used to treat overactive bladder by patients who do not respond to or who cannot tolerate the side effects of other medications. It helps to reduce leaking of urine, feeling of needing to urinate right away, and frequent trips to the bathroom. It is also used to treat severe underarm sweating and drooling/excess saliva. Botulinum toxin works by blocking the chemicals that turn on the sweat and salivary glands. Botulinum toxin is not a cure, and your symptoms will gradually return as the medication wears off.
How is this Solstice Neurosciences, Llc product billed for insurance claims?
For medical billing and reimbursement, this package follows the 11-digit CMS format: 10454071010. Quantities are measured in per "ml or milliliter", products billed per milliliter are usually products measured by liquid volume.. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.
11-Digit Code Conversion
Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:
Note: The zero is added to the Product segment to maintain the 5-4-2 structure.
