Neotuss Plus Liquid
NDC Package 12539-779-01

View Billable Units, 11-Digit Conversion Format, and RxNorm mappings
Table of Contents
    1. Package Information
    2. Other Packages
    3. Frequently Asked Questions

Package Information

Neotuss Plus (dextromethorphan hbr, chlorpheniramine maleate, phenylephrine hcl) liquids is adults and children over 12 years of age: One teaspoonful (5 mL) every 6-8 hours; do not exceed 4 teaspoonfuls in 24 hours period.Children 6-12 years of age: 1/2 teaspoonful (2.5 mL) every 6-8 hours; do not exceed 2 teaspoonfuls in 24 hours period. This formulation utilizes a liquid delivery system. Marketed by Doral Pharmamedics Inc Dba A.g. Marin Pharmaceuticals, this product is identified by NDC 12539-779 and is authorized under FDA application M012.

Identification & Billing

NDC Package Code
12539-779-01
Package Description
30 mL in 1 BOTTLE
Product Code
12539-779
11-Digit Billing Format
12539077901
RxNorm Crosswalk
  • RxCUI: 2167750 - chlorpheniramine maleate 4 MG / dextromethorphan HBr 30 MG / phenylephrine HCl 7.5 MG in 5 mL Oral Solution
  • RxCUI: 2167750 - chlorpheniramine maleate 0.8 MG/ML / dextromethorphan hydrobromide 6 MG/ML / phenylephrine hydrochloride 1.5 MG/ML Oral Solution
  • RxCUI: 2167750 - chlorpheniramine maleate 4 MG / dextromethorphan HBr 30 MG / phenylephrine HCl 7.5 MG per 5 ML Oral Solution

Clinical Specifications

Proprietary Name
Neotuss Plus
Non-Proprietary Name
Dextromethorphan Hbr, Chlorpheniramine Maleate, Phenylephrine Hcl
Substance Name
Chlorpheniramine Maleate; Dextromethorphan Hydrobromide; Phenylephrine Hydrochloride
Dosage Form
Liquid - A dosage form consisting of a pure chemical in its liquid1 state. This dosage form term should not be applied to solutions.
Administration Route
  • Oral - Administration to or by way of the mouth.
  • Oral - Administration to or by way of the mouth.
Active Ingredient(s)
Pharmacologic Class
Usage Information
Adults and children over 12 years of age: One teaspoonful (5 mL) every 6-8 hours; do not exceed 4 teaspoonfuls in 24 hours period.Children 6-12 years of age: 1/2 teaspoonful (2.5 mL) every 6-8 hours; do not exceed 2 teaspoonfuls in 24 hours period. Children under 6 years of age: Ask a doctor.Temporarily relieves cough due to minor throat and bronchial irritations associated with the common cold or inhaled irritants. Helps thin bronchial passageways of bothersome mucus.Temporarily relieves nasal congestion due to the common cold, sinusitis, hay fever or other respiratory allergies.Temporarily relieves sneezing, itching of the nose or throat, and itchy watery eyes due to hay fever or other respiratory allergies.

Regulatory & Marketing

Labeler Name
Doral Pharmamedics Inc Dba A.g. Marin Pharmaceuticals
Product Type
Human Otc Drug
FDA Application #
M012
Marketing Category
OTC MONOGRAPH DRUG -
Start Marketing Date
03-06-2025
Listing Expiration
12-31-2026
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Other Available Packages

The following commercial packages are registered under the same Product NDC (12539-779). Click a package code to view its specific billing and regulatory data.

12539-779-16
474 mL in 1 BOTTLE

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 12539-779-01 identifies a specific commercial package of 30 ml in 1 bottle of Neotuss Plus, a human over the counter drug labeled by Doral Pharmamedics Inc Dba A.g. Marin Pharmaceuticals. This liquid is formulated for oral use and contains chlorpheniramine maleate; dextromethorphan hydrobromide; phenylephrine hydrochloride as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Doral Pharmamedics Inc Dba A.g. Marin Pharmaceuticals on March 06, 2025. The current certification is valid through December 31, 2026.

How is this Doral Pharmamedics Inc Dba A.g. Marin Pharmaceuticals product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 12539077901. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (5-3-2)
12539-779-01
11-Digit CMS (5-4-2)
12539-0779-01

Note: The zero is added to the Product segment to maintain the 5-4-2 structure.