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  5. NDC Package Code: 13533-690-25 Plasbumin

NDC Package 13533-690-25 Plasbumin

Albumin (human) Solution Intravenous - View Billable Units, 11-Digit Format, RxNorm

Table of Contents

    1. Package Information
    2. NDC HCPCS Crosswalk
    3. Other Packages
    4. Frequently Asked Questions

Package Information

Find all the important details about this NDC Package code, including the 11-Digit NDC Billing number, billing units, wholesale price, RxNorm crosswalk, active ingredients, pharmacologic clasess, etc.

NDC Package Code:
13533-690-25
Package Description:
1 VIAL in 1 CARTON / 250 mL in 1 VIAL (13533-690-26)
Product Code:
13533-690
Proprietary Name:
Plasbumin
Non-Proprietary Name:
Albumin (human)
Substance Name:
Albumin Human
Usage Information:
Emergency Treatment of Hypovolemic ShockPlasbumin-5 is iso-oncotic with normal plasma and on intravenous infusion will expand the circulating blood volume by an amount approximately equal to the volume infused. In conditions associated mainly with a volume deficit, albumin is best administered as a 5% solution (Plasbumin-5); but where there is an oncotic deficit, Albumin (Human) 25%, USP (Plasbumin®-25) may be preferred. This is also an important consideration where the treatment of the shock state has been delayed. If Plasbumin-25 is used, appropriate additional crystalloid should be administered.(1)Crystalloid solutions in volumes several times greater than that of Plasbumin-5 may be effective in treating shock in younger individuals who have no preexisting illness at the time of the incident. Older patients, especially those with preexisting debilitating conditions, or those in whom the shock is caused by a medical disorder, or where the state of shock has existed for some time before active therapy could be instituted, may not tolerate hypoalbuminemia as well.(1)Removal of ascitic fluid from a patient with cirrhosis may cause changes in cardiovascular function and even result in hypovolemic shock. In such circumstances, the use of albumin infusion may be required to support the blood volume.(1)Burn TherapyAn optimal therapeutic regimen with respect to the administration of colloids, crystalloids, and water following extensive burns has not been established. During the first 24 hours after sustaining thermal injury, large volumes of crystalloids are infused to restore the depleted extracellular fluid volume. Beyond 24 hours, albumin can be used to maintain plasma colloid osmotic pressure. Plasbumin-25 may be preferred for this purpose.(1)Cardiopulmonary Bypass(1)With the relatively small priming volume required with modern pumps, preoperative dilution of the blood using albumin and crystalloid has been shown to be safe and well-tolerated. Although the limit to which the hematocrit and plasma protein concentration can be safely lowered has not been defined, it is common practice to adjust the albumin and crystalloid pump prime to achieve a hematocrit of 20% and a plasma albumin concentration of 2.5 g per 100 mL in the patient.Acute Liver Failure(1)In the uncommon situation of rapid loss of liver function, with or without coma, administration of albumin may serve the double purpose of supporting the colloid osmotic pressure of the plasma as well as binding excess plasma bilirubin.Sequestration of Protein Rich Fluids(2)This occurs in such conditions as acute peritonitis, pancreatitis, mediastinitis, and extensive cellulitis. The magnitude of loss into the third space may require treatment of reduced volume or oncotic activity with an infusion of albumin.Situations in Which Albumin Administration is Not Warranted(1)In chronic nephrosis, infused albumin is promptly excreted by the kidneys with no relief of the chronic edema or effect on the underlying renal lesion. It is of occasional use in the rapid “priming” diuresis of nephrosis. Similarly, in hypoproteinemic states associated with chronic cirrhosis, malabsorption, protein losing enteropathies, pancreatic insufficiency, and undernutrition, the infusion of albumin as a source of protein nutrition is not justified.
11-Digit NDC Billing Format:
13533069025
Billing Unit:
ML - Billing unit of "milliliter" is used when a product is measured by its liquid volume.
NDC to RxNorm Crosswalk:
  • RxCUI: 1741403 - albumin human 5 % in 50 ML Injection
  • RxCUI: 1741403 - 50 ML albumin human, USP 50 MG/ML Injection
  • RxCUI: 1741403 - albumin human 2.5 GM per 50 ML Injection
  • RxCUI: 1741403 - albumin human 5 % per 50 ML Injection
  • RxCUI: 1741420 - albumin human 5 % in 250 ML Injection
    • Product Type:
    Plasma Derivative
    Labeler Name:
    Grifols Usa, Llc
    Dosage Form:
    Solution - A clear, homogeneous liquid1 dosage form that contains one or more chemical substances dissolved in a solvent or mixture of mutually miscible solvents.
    Administration Route(s):
  • Intravenous - Administration within or into a vein or veins.
    • Active Ingredient(s):
  • ALBUMIN HUMAN 2.5 g/50mL
    • Pharmacologic Class(es):
  • Human Serum Albumin - [EPC] (Established Pharmacologic Class)
  • Increased Intravascular Volume - [PE] (Physiologic Effect)
  • Increased Oncotic Pressure - [PE] (Physiologic Effect)
  • Osmotic Activity - [MoA] (Mechanism of Action)
  • Serum Albumin - [Chemical/Ingredient]
    • Sample Package:
    No
    FDA Application Number:
    BLA101138
    Marketing Category:
    BLA - A product marketed under an approved Biologic License Application.
    Start Marketing Date:
    09-26-1994
    Listing Expiration Date:
    12-31-2024
    Exclude Flag:
    N
    Code Structure:

    The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

    * Please review the disclaimer below.

    NDC HCPCS Crosswalk

    This crosswalk is intended to help the public understand which drug products (identified by NDCs) are assigned to which HCPCS billing codes.

    NDC 13533-690-25 HCPCS crosswalk information with package details and bill units information.

    NDC Billing CodeHCPCS CodeHCPCS Code Desc.DosagePackage SizePackage QuantityBillable UnitsBillable Units / Pkg
    13533069025P9041Albumin (human),5%, 50ml50 ML250155
    13533069025P9045Albumin (human), 5%, 250 ml250 ML250111

    * Please review the disclaimer below.

    Other Product Packages

    The following packages are also available for this product:

    NDC Package CodePackage Description
    13533-690-201 VIAL in 1 CARTON / 50 mL in 1 VIAL (13533-690-21)
    13533-690-271 VIAL in 1 CARTON / 500 mL in 1 VIAL (13533-690-28)

    * Please review the disclaimer below.

    Frequently Asked Questions

    What is NDC 13533-690-25?

    The NDC Packaged Code 13533-690-25 is assigned to a package of 1 vial in 1 carton / 250 ml in 1 vial (13533-690-26) of Plasbumin, a plasma derivative labeled by Grifols Usa, Llc. The product's dosage form is solution and is administered via intravenous form.

    Is NDC 13533-690 included in the NDC Directory?

    Yes, Plasbumin with product code 13533-690 is active and included in the NDC Directory. The product was first marketed by Grifols Usa, Llc on September 26, 1994 and its listing in the NDC Directory is set to expire on December 31, 2024 if the product is not updated or renewed by the manufacturer.

    What is the NDC billing unit for package 13533-690-25?

    The contents of this package are billed per "ml or milliliter", products billed per milliliter are usually products measured by liquid volume.

    What is the 11-digit format for NDC 13533-690-25?

    The 11-digit format is 13533069025. The 11-digit billing format might be required by the Centers for Medicare & Medicaid Services (CMS) and other payers in billing claim forms.

    This package code is originally configured in a 5-3-2 segment 10-digit format and by adding a zero within the original NDC package code we can obtain the converted 11-digit format in a 5-4-2 segment configuration. The table below shows the 11-digit code conversion:

    10-Digit Format10-Digit Original Code11-Digit Format11-Digit Code
    5-3-213533-690-255-4-213533-0690-25