Chlorhexidine Gluconate Solution
Pricing Report NDC 16571-111-48

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Chlorhexidine Gluconate (NDC 16571-111-48) is $0.01901 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human over the counter drug provided by Rising Pharma Holdings, Inc., this medication is distributed in a 473 mL in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.01901
Per ML

Effective Date
Jun 17, 2026
Billable Units
473 ML
Estimated Package Price
$8.99
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
473 mL in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Dec 2023, the NADAC wholesale price for (NDC ) has moved within a range of $0.01743 to $0.05495 per ML. Over this 2 years and 6 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.0232 - $0.0550
Market Volatility
136.65% Variance
Latest Trend
0.20%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.04399 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 17, 2026 $0.02932 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 17, 2026 $0.01901 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 20, 2026 $0.04408 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 20, 2026 $0.02859 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 20, 2026 $0.01883 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 22, 2026 $0.04680 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 22, 2026 $0.02945 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 22, 2026 $0.01928 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 18, 2026 $0.04723 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 18, 2026 $0.03024 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 18, 2026 $0.01787 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 18, 2026 $0.04741 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 18, 2026 $0.03105 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 18, 2026 $0.01787 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 21, 2026 $0.04696 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 21, 2026 $0.03106 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 21, 2026 $0.01743 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 17, 2025 $0.04981 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 17, 2025 $0.03056 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 17, 2025 $0.01839 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 19, 2025 $0.05153 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 19, 2025 $0.03026 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 19, 2025 $0.01767 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 22, 2025 $0.05278 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 22, 2025 $0.02988 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 22, 2025 $0.01828 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 17, 2025 $0.05334 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 17, 2025 $0.03040 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 17, 2025 $0.01971 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 20, 2025 $0.05172 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 20, 2025 $0.03047 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 20, 2025 $0.02168 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 23, 2025 $0.05171 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 23, 2025 $0.03087 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 23, 2025 $0.02250 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 18, 2025 $0.05083 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 18, 2025 $0.03103 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 18, 2025 $0.02237 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 21, 2025 $0.05326 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 21, 2025 $0.03139 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 21, 2025 $0.02262 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 23, 2025 $0.05257 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 23, 2025 $0.03146 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 23, 2025 $0.02266 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 19, 2025 $0.05202 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 19, 2025 $0.03124 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 19, 2025 $0.02298 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2025 $0.05136 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2025 $0.03088 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 19, 2025 $0.02310 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 22, 2025 $0.05067 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 22, 2025 $0.03008 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jan 22, 2025 $0.02338 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 18, 2024 $0.05245 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 18, 2024 $0.02909 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 18, 2024 $0.02424 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Nov 20, 2024 $0.02907 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 23, 2024 $0.05488 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 23, 2024 $0.05488 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Oct 23, 2024 $0.02794 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 23, 2024 $0.02497 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Oct 23, 2024 $0.02497 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Sep 18, 2024 $0.04773 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 18, 2024 $0.02558 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Sep 18, 2024 $0.02379 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 21, 2024 $0.04692 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 21, 2024 $0.02659 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Aug 21, 2024 $0.02318 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 17, 2024 $0.04353 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 17, 2024 $0.02644 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jul 17, 2024 $0.02209 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 19, 2024 $0.04772 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 19, 2024 $0.02612 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Jun 19, 2024 $0.02222 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 22, 2024 $0.04572 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 22, 2024 $0.02612 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
May 22, 2024 $0.02221 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 17, 2024 $0.05217 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Apr 17, 2024 $0.02346 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Mar 20, 2024 $0.02323 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 21, 2024 $0.05495 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Feb 21, 2024 $0.05495 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Dec 20, 2023 $0.02322 MLC/I - Chain or Independent PharmacyCode 1, 5, 6G - Generic
Dec 20, 2023 $0.02322 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic
Dec 13, 2023 $0.02359 MLC/I - Chain or Independent PharmacyCode 4, 5, 6G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026