Buprenorphine Hydrochloride And Naloxone Hydrochloride Dihydrate Tablet
Pricing Report NDC 16729-549-10

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Buprenorphine Hydrochloride And Naloxone Hydrochloride Dihydrate (NDC 16729-549-10) is $0.41234 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Accord Healthcare, Inc, this medication is distributed in a 30 TABLET in 1 BOTTLE, PLASTIC configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.41234
Per EA

Effective Date
Jun 17, 2026
Billable Units
30 EA
Estimated Package Price
$12.37
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
30 TABLET in 1 BOTTLE, PLASTIC
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Feb 2021, the NADAC wholesale price for (NDC ) has moved within a range of $0.37404 to $1.06544 per EA. Over this 5 years and 4 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.3740 - $1.0654
Market Volatility
184.85% Variance
Latest Trend
4.39%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.41234 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $0.43127 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $0.46976 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $0.48139 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $0.47749 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $0.46996 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $0.47405 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $0.48790 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $0.49557 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $0.52245 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $0.54631 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $0.54317 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $0.52145 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $0.49804 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $0.49749 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $0.49860 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $0.47749 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $0.43661 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2024 $0.46400 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 20, 2024 $0.37404 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 23, 2024 $0.59811 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 18, 2024 $0.59147 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 21, 2024 $0.62535 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 17, 2024 $0.39457 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 19, 2024 $0.63776 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 22, 2024 $0.43913 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 17, 2024 $0.42366 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 20, 2024 $0.67958 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 21, 2024 $0.53821 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 17, 2024 $0.58886 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 20, 2023 $0.71700 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 22, 2023 $0.66495 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 18, 2023 $0.63617 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 20, 2023 $0.62646 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 23, 2023 $0.56477 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 19, 2023 $0.53673 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 21, 2023 $0.61115 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 17, 2023 $0.54574 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 19, 2023 $0.46591 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 22, 2023 $0.53576 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 22, 2023 $0.64329 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 18, 2023 $0.59087 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 21, 2022 $0.66543 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 23, 2022 $0.75219 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 19, 2022 $0.74316 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 21, 2022 $0.79179 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 17, 2022 $0.68625 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 20, 2022 $0.73992 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 22, 2022 $0.62666 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 18, 2022 $0.70938 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 20, 2022 $0.64539 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 23, 2022 $0.72296 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 23, 2022 $0.79030 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 19, 2022 $0.84418 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 22, 2021 $0.74447 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 17, 2021 $0.86031 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 20, 2021 $0.70981 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 22, 2021 $0.86537 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 18, 2021 $0.93506 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 21, 2021 $1.06544 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 23, 2021 $0.86417 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 19, 2021 $1.02944 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 21, 2021 $1.02010 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 17, 2021 $1.03544 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 17, 2021 $0.95005 EAC/I - Chain or Independent PharmacyCode 1G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026