Naloxone Hydrochloride
Pricing Report NDC 17478-042-10
Current Package Pricing Information
The latest wholesale acquisition cost for Naloxone Hydrochloride (NDC 17478-042-10) is $6.48820 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jul 20, 2022.
As a provided by Akorn, this medication is distributed in a 1 VIAL, MULTI-DOSE in 1 CARTON / 10 mL in 1 VIAL, MULTI-DOSE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.
NADAC Pricing Summary
NADAC pricing snapshot for this package NDC
Acquisition Cost $6.48820 Per ML
The NADAC was calculated based on package size.
Historical Pricing Trends & Acquisition Cost Benchmarks
Since Aug 2019, the NADAC wholesale price for (NDC ) has moved within a range of $6.48820 to $12.18386 per ML. Over this 2 years and 10 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.
$6.4882 - $12.1839
87.78% Variance
42.12%
| Date | Unit Price | Unit | Source | Method | Rate |
|---|---|---|---|---|---|
| Jul 20, 2022 | $6.48820 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Jul 20, 2022 | $6.48820 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Mar 17, 2021 | $11.20940 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Mar 17, 2021 | $11.20940 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Sep 18, 2019 | $12.08620 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
| Sep 18, 2019 | $12.08620 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | G - Generic |
| Aug 21, 2019 | $12.18386 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | G - Generic |
Pricing Methodology Legend
- Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
- Code 4: The NADAC was carried forward from the previous file.
- Code 5: The NADAC was calculated based on package size.
Understanding NADAC Pricing Data
The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.
Important Price Distinction:
The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.
NADAC Pricing Data Last Updated on: July 08, 2026