Ketoconazole Cream
Pricing Report NDC 21922-025-07

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Ketoconazole (NDC 21922-025-07) is $0.16332 per GM. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Encube Ethicals, Inc., this medication is distributed in a 1 TUBE in 1 CARTON / 60 g in 1 TUBE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.16332
Per GM

Effective Date
Jun 17, 2026
Billable Units
60 GM
Estimated Package Price
$9.80
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 TUBE in 1 CARTON / 60 g in 1 TUBE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jun 2021, the NADAC wholesale price for (NDC ) has moved within a range of $0.13846 to $0.60282 per GM. Over this 4 years and 11 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.2119 - $0.6028
Market Volatility
184.44% Variance
Latest Trend
2.14%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.31067 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2026 $0.25617 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2026 $0.16332 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.30415 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.25087 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.17057 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.31394 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.25290 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.17988 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.31358 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.24861 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.18377 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.32417 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.26131 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.18533 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.33059 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.27092 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.18396 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.34455 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.27261 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.18807 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.34942 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.27194 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.18484 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.35141 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.27445 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.18542 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $0.33809 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $0.28023 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $0.18101 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $0.32435 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $0.28332 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $0.18366 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $0.30217 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $0.27733 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $0.18201 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.29974 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.26526 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.18332 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.33369 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.25981 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.17783 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $0.35521 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $0.25753 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $0.17564 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $0.37439 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $0.26518 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $0.17334 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.31513 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.23948 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.16707 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.27805 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.21510 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.15335 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.24434 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.21481 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.15620 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.24108 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.19484 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.13846 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.26580 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.26008 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.18021 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.26900 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.24405 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.19631 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.27276 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.24721 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.19351 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.21193 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.20499 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.15598 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $0.25077 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $0.23617 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $0.19397 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $0.21580 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $0.21346 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $0.16428 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $0.22276 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $0.22166 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $0.18285 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2024 $0.29872 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2024 $0.26853 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2024 $0.22253 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2024 $0.25951 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2024 $0.24431 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2024 $0.20459 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 17, 2024 $0.28572 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 17, 2024 $0.27595 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 17, 2024 $0.20544 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $0.26386 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $0.24669 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $0.19327 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2023 $0.25619 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2023 $0.27712 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2023 $0.21918 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 18, 2023 $0.26576 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 18, 2023 $0.27239 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 18, 2023 $0.20280 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 20, 2023 $0.28592 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 20, 2023 $0.26224 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 20, 2023 $0.24138 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 23, 2023 $0.25931 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 23, 2023 $0.27224 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 23, 2023 $0.20706 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 19, 2023 $0.26224 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 19, 2023 $0.25171 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 19, 2023 $0.22099 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 21, 2023 $0.26894 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 21, 2023 $0.24949 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 21, 2023 $0.20280 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 17, 2023 $0.28132 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 17, 2023 $0.28812 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 17, 2023 $0.20634 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 19, 2023 $0.26790 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 19, 2023 $0.25452 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 19, 2023 $0.20710 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 22, 2023 $0.29591 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 22, 2023 $0.25940 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 22, 2023 $0.21463 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 22, 2023 $0.29027 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 22, 2023 $0.27632 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 22, 2023 $0.22254 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 18, 2023 $0.32363 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 18, 2023 $0.27124 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 18, 2023 $0.20986 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2022 $0.30519 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2022 $0.28396 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2022 $0.21800 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 23, 2022 $0.31375 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 23, 2022 $0.27836 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 23, 2022 $0.22320 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 19, 2022 $0.33098 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 19, 2022 $0.29370 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 19, 2022 $0.24607 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 21, 2022 $0.30256 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 21, 2022 $0.33477 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 21, 2022 $0.24072 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2022 $0.32906 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2022 $0.31794 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2022 $0.24642 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 20, 2022 $0.34271 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 20, 2022 $0.35919 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 20, 2022 $0.28369 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 22, 2022 $0.37909 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 22, 2022 $0.36209 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 22, 2022 $0.30462 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 18, 2022 $0.50062 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 18, 2022 $0.37528 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 18, 2022 $0.31446 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2022 $0.48918 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2022 $0.41841 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2022 $0.35105 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 23, 2022 $0.53088 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 23, 2022 $0.43567 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 23, 2022 $0.36478 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 23, 2022 $0.49034 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 23, 2022 $0.47799 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 23, 2022 $0.33131 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 19, 2022 $0.50162 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 19, 2022 $0.46447 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 19, 2022 $0.35941 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 22, 2021 $0.47318 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 22, 2021 $0.42659 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 22, 2021 $0.31478 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 17, 2021 $0.59750 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 17, 2021 $0.49118 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 17, 2021 $0.36590 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 20, 2021 $0.53268 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 20, 2021 $0.51324 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 20, 2021 $0.37355 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 22, 2021 $0.60161 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 22, 2021 $0.51842 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 22, 2021 $0.36406 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 18, 2021 $0.60282 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 18, 2021 $0.56023 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 18, 2021 $0.39323 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 21, 2021 $0.58343 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 21, 2021 $0.57220 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 21, 2021 $0.42312 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 23, 2021 $0.56977 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 23, 2021 $0.54157 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 23, 2021 $0.33674 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026