Tretinoin Gel
Pricing Report NDC 21922-043-40

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Tretinoin (NDC 21922-043-40) is $10.17859 per GM. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Encube Ethicals, Inc., this medication is distributed in a 1 BOTTLE, PUMP in 1 CARTON / 50 g in 1 BOTTLE, PUMP configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$10.17859
Per GM

Effective Date
Jun 17, 2026
Billable Units
50 GM
Estimated Package Price
$508.93
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 BOTTLE, PUMP in 1 CARTON / 50 g in 1 BOTTLE, PUMP
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Apr 2024, the NADAC wholesale price for (NDC ) has moved within a range of $6.94020 to $12.62454 per GM. Over this 2 years and 2 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$6.9402 - $12.6245
Market Volatility
81.90% Variance
Latest Trend
16.87%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $10.17859 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $8.70916 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $7.88318 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $6.98820 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $6.94020 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $8.02745 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $8.96868 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $10.29300 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $10.96521 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $11.98642 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $12.62454 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $12.20324 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $11.73826 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $11.51045 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $11.30395 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $10.89528 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $10.23970 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $10.35368 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $9.97327 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $10.71591 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $9.04596 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $8.73781 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $9.12899 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $9.17113 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $9.05123 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $8.73763 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $10.54160 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026