Clobetasol Propionate Solution
Pricing Report NDC 21922-061-22

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Clobetasol Propionate (NDC 21922-061-22) is $0.25035 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Encube Ethicals, Inc., this medication is distributed in a 1 BOTTLE in 1 CARTON / 25 mL in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.25035
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 BOTTLE in 1 CARTON / 25 mL in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jul 2024, the NADAC wholesale price for (NDC ) has moved within a range of $0.11487 to $0.47143 per ML. Over this 1 year and 11 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.2504 - $0.4714
Market Volatility
88.31% Variance
Latest Trend
0.01%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.25035 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2026 $0.11723 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.25037 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.11487 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.25833 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.11575 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.26156 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.11959 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.26001 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.12039 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.26425 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.12394 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.27795 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.12490 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.29555 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.14214 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.30438 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.16554 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $0.29729 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $0.18291 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $0.29905 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $0.19172 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $0.28031 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $0.18703 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.27696 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.18053 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.29935 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.17379 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $0.33343 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $0.17518 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $0.34516 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $0.17677 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.30610 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.17286 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.30269 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.17183 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.35855 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.18278 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.34568 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.18132 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.47143 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.20193 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.44442 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.25059 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.44632 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.22338 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.32812 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.19097 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 03, 2024 $0.39466 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 03, 2024 $0.17617 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026