Tretinoin Cream
Pricing Report NDC 21922-079-25

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

The current wholesale acquisition cost for Tretinoin (NDC 21922-079-25) is $0.57199 per GM. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Encube Ethicals, Inc., this medication is distributed in a 1 TUBE in 1 CARTON / 20 g in 1 TUBE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.57199
Per GM

Pricing Unit
Per GM Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Jun 17, 2026
Billable Units
20 GM
Estimated Package Price
$11.44
Data Status
As of Jul 08, 2026
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
G - Generic
Package NDC
21922-079-25
Description
1 TUBE in 1 CARTON / 20 g in 1 TUBE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Mar 2026, the NADAC wholesale price for (NDC ) has moved within a range of $0.48511 to $0.96234 per GM. Over this 3 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.4851 - $0.8884
Market Volatility
83.14% Variance
Latest Trend
10.41%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.48511 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2026 $0.57199 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.54145 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.62972 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.67072 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.75086 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.79702 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.87441 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 04, 2026 $0.88844 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 04, 2026 $0.96234 GMC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026