1. Home
  2. Labeler Index
  3. Encube Ethicals Private Limited
  4. 21922-087
  5. NDC Package Code: 21922-087-52 Estradiol Gel

NDC Package 21922-087-52 Estradiol Gel

Estradiol Gel Topical - View Billable Units, 11-Digit Format, RxNorm

Table of Contents

    1. Package Information
    2. Frequently Asked Questions

Package Information

Find all the important details about this NDC Package code, including the 11-Digit NDC Billing number, billing units, wholesale price, RxNorm crosswalk, active ingredients, pharmacologic clasess, etc.

NDC Package Code:
21922-087-52
Package Description:
30 PACKET in 1 CARTON / .5 g in 1 PACKET
Product Code:
21922-087
Proprietary Name:
Estradiol Gel
Non-Proprietary Name:
Estradiol
Substance Name:
Estradiol
Usage Information:
This medication is a female hormone (estrogen). It is used by women to help reduce symptoms of menopause (such as hot flashes, vaginal dryness). These symptoms are caused by the body making less estrogen. If you are using this medication to treat symptoms only in and around the vagina, products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. This medication may also be used by women who are not able to produce enough estrogen (for example, due to hypogonadism, primary ovarian failure). Certain estrogen products may also be used by women after menopause to prevent bone loss (osteoporosis). However, there are other medications (such as raloxifene, bisphosphonates including alendronate) that are also effective in preventing bone loss and may be safer. These medications should be considered for use before estrogen treatment.
11-Digit NDC Billing Format:
21922008752
NDC to RxNorm Crosswalk:
Product Type:
Human Prescription Drug
Labeler Name:
Encube Ethicals Private Limited
Dosage Form:
Gel - A semisolid3 dosage form that contains a gelling agent to provide stiffness to a solution or a colloidal dispersion.4 A gel may contain suspended particles.
Administration Route(s):
Topical - Administration to a particular spot on the outer surface of the body. The E2B term TRANSMAMMARY is a subset of the term TOPICAL.
Active Ingredient(s):
ESTRADIOL .5 mg/.5g
Pharmacologic Class(es):
Sample Package:
No
FDA Application Number:
ANDA218507
Marketing Category:
ANDA - A product marketed under an approved Abbreviated New Drug Application.
Start Marketing Date:
03-10-2025
Listing Expiration Date:
12-31-2026
Exclude Flag:
N
Code Structure:

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the disclaimer below.

Frequently Asked Questions

What is NDC 21922-087-52?

The NDC Packaged Code 21922-087-52 is assigned to a package of 30 packet in 1 carton / .5 g in 1 packet of Estradiol Gel, a human prescription drug labeled by Encube Ethicals Private Limited. The product's dosage form is gel and is administered via topical form.

Is NDC 21922-087 included in the NDC Directory?

Yes, Estradiol Gel with product code 21922-087 is active and included in the NDC Directory. The product was first marketed by Encube Ethicals Private Limited on March 10, 2025 and its listing in the NDC Directory is set to expire on December 31, 2026 if the product is not updated or renewed by the manufacturer.

What is the 11-digit format for NDC 21922-087-52?

The 11-digit format is 21922008752. The 11-digit billing format might be required by the Centers for Medicare & Medicaid Services (CMS) and other payers in billing claim forms.

This package code is originally configured in a 5-3-2 segment 10-digit format and by adding a zero within the original NDC package code we can obtain the converted 11-digit format in a 5-4-2 segment configuration. The table below shows the 11-digit code conversion:

10-Digit Format10-Digit Original Code11-Digit Format11-Digit Code
5-3-221922-087-525-4-221922-0087-52