Brevital Sodium Injection, Powder, Lyophilized, For Solution
NDC Package 42023-105-01

View Billable Units, 11-Digit Conversion Format, and RxNorm mappings
Table of Contents
    1. Package Information
    2. Frequently Asked Questions

Package Information

Brevital Sodium (methohexital sodium) injection is bREVITAL can be used in adults as follows:1.For intravenous induction of anesthesia prior to the use of other general anesthetic agents.2.For intravenous induction of anesthesia and as an adjunct to subpotent inhalational anesthetic agents (such as nitrous oxide in oxygen) for short surgical procedures; BREVITAL may be given by infusion or intermittent injection.3.For use along with other parenteral agents, usually narcotic analgesics, to supplement subpotent inhalational anesthetic agents (such as nitrous oxide in oxygen) for longer surgical procedures.4.As intravenous anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful stimuli (see WARNINGS).5.As an agent for inducing a hypnotic state.BREVITAL can be used in pediatric patients older than 1 month as follows:1.For rectal or intramuscular induction of anesthesia prior to the use of other general anesthetic agents.2.For rectal or intramuscular induction of anesthesia and as an adjunct to subpotent inhalational anesthetic agents for short surgical procedures.3.As rectal or intramuscular anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful stimuli. This formulation utilizes a injection, powder, lyophilized, for solution delivery system. Marketed by Par Health Usa, Llc, this product is identified by NDC 42023-105 and is authorized under FDA application NDA011559.

Identification & Billing

NDC Package Code
42023-105-01
Package Description
1 VIAL in 1 CARTON / 1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION in 1 VIAL
Product Code
42023-105
11-Digit Billing Format
42023010501
Billing Unit
EA - Billing unit of "each" is used when the product is dispensed in discreet units.
Units Per Package
1 EA
RxNorm Crosswalk
  • RxCUI: 1244233 - methohexital sodium Variable Concentration Multi-Use Injectable Solution
  • RxCUI: 1244233 - methohexital sodium 50 MG/ML Injectable Solution
  • RxCUI: 1244638 - Brevital Sodium Variable Concentration Multi-Use Injectable Solution
  • RxCUI: 1244638 - methohexital sodium 50 MG/ML Injectable Solution [Brevital]
  • RxCUI: 1244638 - Brevital 50 MG/ML Injectable Solution

Clinical Specifications

Proprietary Name
Brevital Sodium
Non-Proprietary Name
Methohexital Sodium
Substance Name
Methohexital Sodium
Dosage Form
Injection, Powder, Lyophilized, For Solution - A dosage form intended for the solution prepared by lyophilization ("freeze drying"), a process which involves the removal of water from products in the frozen state at extremely low pressures; this is intended for subsequent addition of liquid to create a solution that conforms in all respects to the requirements for Injections.
Administration Route
  • Intramuscular - Administration within a muscle.
  • Intravenous - Administration within or into a vein or veins.
  • Rectal - Administration to the rectum.
Active Ingredient(s)
METHOHEXITAL SODIUM 500 mg/1
Pharmacologic Class
Usage Information
BREVITAL can be used in adults as follows:1.For intravenous induction of anesthesia prior to the use of other general anesthetic agents.2.For intravenous induction of anesthesia and as an adjunct to subpotent inhalational anesthetic agents (such as nitrous oxide in oxygen) for short surgical procedures; BREVITAL may be given by infusion or intermittent injection.3.For use along with other parenteral agents, usually narcotic analgesics, to supplement subpotent inhalational anesthetic agents (such as nitrous oxide in oxygen) for longer surgical procedures.4.As intravenous anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful stimuli (see WARNINGS).5.As an agent for inducing a hypnotic state.BREVITAL can be used in pediatric patients older than 1 month as follows:1.For rectal or intramuscular induction of anesthesia prior to the use of other general anesthetic agents.2.For rectal or intramuscular induction of anesthesia and as an adjunct to subpotent inhalational anesthetic agents for short surgical procedures.3.As rectal or intramuscular anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful stimuli.
DEA Schedule
Schedule IV (CIV) Substances

Regulatory & Marketing

Labeler Name
Par Health Usa, Llc
Product Type
Human Prescription Drug
FDA Application #
NDA011559
Marketing Category
NDA - A product marketed under an approved New Drug Application.
Start Marketing Date
11-01-2007
Listing Expiration
12-31-2027
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 42023-105-01 identifies a specific commercial package of 1 vial in 1 carton / 1 injection, powder, lyophilized, for solution in 1 vial of Brevital Sodium, a human prescription drug labeled by Par Health Usa, Llc. This product is billed for "EA" each discreet unit and contains an estimated amount of 1 billable units per package. This injection, powder, lyophilized, for solution is formulated for intramuscular; intravenous; rectal use and contains methohexital sodium as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Par Health Usa, Llc on November 01, 2007. The current certification is valid through December 31, 2027.

How is this Par Health Usa, Llc product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 42023010501. Quantities are measured in per "each", products billed on a per each basis are usually products dispensed in discreet units.. There are 1 total billable units per package. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (5-3-2)
42023-105-01
11-Digit CMS (5-4-2)
42023-0105-01

Note: The zero is added to the Product segment to maintain the 5-4-2 structure.