Protriptyline Hydrochloride Tablet, Film Coated
Pricing Report NDC 42794-004-02

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Protriptyline Hydrochloride (NDC 42794-004-02) is $2.55828 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Sigmapharm Laboratories, Llc, this medication is distributed in a 100 TABLET, FILM COATED in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$2.55828
Per EA

Effective Date
Jun 17, 2026
Billable Units
100 EA
Estimated Package Price
$255.83
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
100 TABLET, FILM COATED in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Feb 2021, the NADAC wholesale price for (NDC ) has moved within a range of $2.37230 to $3.81785 per EA. Over this 5 years and 4 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$2.3723 - $3.8179
Market Volatility
60.93% Variance
Latest Trend
3.12%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $2.55828 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $2.64072 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $2.69829 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $2.82608 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $2.95386 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $3.02852 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $2.95838 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $2.87400 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $2.86652 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $2.81139 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $2.76599 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $2.76661 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $2.74278 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $2.75239 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $2.65134 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $3.71785 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $3.81785 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $3.77138 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2024 $3.70194 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 20, 2024 $3.67844 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 23, 2024 $3.50955 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 18, 2024 $3.14333 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 21, 2024 $3.08216 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 17, 2024 $2.66273 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 19, 2024 $2.43918 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 22, 2024 $2.37230 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 17, 2024 $2.40709 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 17, 2021 $2.61989 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 17, 2021 $2.61989 EAC/I - Chain or Independent PharmacyCode 4G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026