Protriptyline Hydrochloride Tablet, Film Coated
Pricing Report NDC 42794-007-02

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Protriptyline Hydrochloride (NDC 42794-007-02) is $2.75123 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Sigmapharm Laboratories, Llc, this medication is distributed in a 100 TABLET, FILM COATED in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$2.75123
Per EA

Effective Date
Jun 17, 2026
Billable Units
100 EA
Estimated Package Price
$275.12
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
100 TABLET, FILM COATED in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since May 2020, the NADAC wholesale price for (NDC ) has moved within a range of $2.08706 to $3.48864 per EA. Over this 6 years period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$2.0871 - $3.4886
Market Volatility
67.16% Variance
Latest Trend
0.70%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $2.75123 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $2.77049 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $2.89287 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $3.04062 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $3.10319 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $3.17753 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $3.09490 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $3.08679 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $2.98568 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $2.88184 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $2.74375 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $2.59090 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $2.46850 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $2.39020 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $2.40979 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $2.41685 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $2.45565 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $2.43507 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2024 $2.44301 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 20, 2024 $2.47793 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 23, 2024 $2.40066 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 18, 2024 $2.24880 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 21, 2024 $2.13411 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 17, 2024 $2.13820 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 19, 2024 $2.11446 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 22, 2024 $2.44134 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 17, 2024 $2.71599 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 20, 2023 $3.21426 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 20, 2023 $3.21426 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Jun 21, 2023 $2.82682 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 21, 2023 $2.82682 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Feb 22, 2023 $3.08567 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 22, 2023 $3.08567 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Jan 18, 2023 $2.60940 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 22, 2022 $2.44917 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 22, 2022 $2.44917 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Jan 19, 2022 $3.06317 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 19, 2022 $3.06317 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Aug 18, 2021 $3.48864 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 18, 2021 $3.48864 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Jul 21, 2021 $3.42292 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 23, 2021 $2.83850 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 17, 2021 $3.21547 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 17, 2021 $3.21547 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Jan 20, 2021 $3.07655 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 20, 2021 $3.07655 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Dec 23, 2020 $2.08706 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 27, 2020 $3.21782 EAC/I - Chain or Independent PharmacyCode 4G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026