Leucovorin Calcium Tablet
Pricing Report NDC 42806-133-21

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Leucovorin Calcium (NDC 42806-133-21) is $1.98422 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Epic Pharma Llc, this medication is distributed in a 12 TABLET in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$1.98422
Per EA

Effective Date
Jun 17, 2026
Billable Units
12 EA
Estimated Package Price
$23.81
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
12 TABLET in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Apr 2022, the NADAC wholesale price for (NDC ) has moved within a range of $1.98422 to $5.53306 per EA. Over this 4 years and 2 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$1.9842 - $5.5331
Market Volatility
178.85% Variance
Latest Trend
1.58%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $1.98422 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 17, 2026 $1.98422 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $2.01608 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $2.01608 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $2.20286 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $2.20286 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $2.37542 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $2.37542 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $2.49746 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $2.49746 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $2.33834 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $2.33834 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $2.27255 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $2.27255 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $2.43574 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $2.43574 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $2.67931 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $2.67931 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $2.97511 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $2.97511 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $3.09601 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $3.09601 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $3.03382 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $3.03382 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $2.97646 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $2.97646 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $2.80176 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $2.80176 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $2.54538 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $2.54538 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $2.34883 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $2.34883 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $2.32958 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $2.32958 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $2.61345 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $2.61345 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2024 $2.90671 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2024 $2.90671 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 20, 2024 $2.83400 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 20, 2024 $2.83400 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 23, 2024 $3.30775 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 23, 2024 $3.30775 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 18, 2024 $3.08029 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 18, 2024 $3.08029 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 21, 2024 $2.71321 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 21, 2024 $2.71321 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 17, 2024 $2.67113 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 17, 2024 $2.67113 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 19, 2024 $2.94196 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 19, 2024 $2.94196 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 22, 2024 $2.78996 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 22, 2024 $2.78996 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 17, 2024 $2.91140 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 17, 2024 $2.91140 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 20, 2024 $4.03875 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 20, 2024 $4.03875 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 20, 2023 $4.17509 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 20, 2023 $4.17509 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Sep 20, 2023 $4.17509 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 20, 2023 $4.17509 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Aug 23, 2023 $4.31322 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 23, 2023 $4.31322 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 17, 2023 $4.29077 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 17, 2023 $4.29077 EAC/I - Chain or Independent PharmacyCode 4G - Generic
May 17, 2023 $4.29077 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 17, 2023 $4.29077 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Feb 22, 2023 $4.36174 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 22, 2023 $4.36174 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Feb 22, 2023 $4.36174 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 22, 2023 $4.36174 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Jan 18, 2023 $4.61863 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 18, 2023 $4.61863 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 21, 2022 $5.53306 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 21, 2022 $5.53306 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 22, 2022 $4.04317 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 22, 2022 $4.04317 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Jun 22, 2022 $4.04317 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 22, 2022 $4.04317 EAC/I - Chain or Independent PharmacyCode 4G - Generic
May 18, 2022 $5.14607 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 18, 2022 $5.14607 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 06, 2022 $5.44565 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Apr 06, 2022 $5.44565 EAC/I - Chain or Independent PharmacyCode 4G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026