Bupropion Hydrochloride Tablet, Extended Release
Pricing Report NDC 42806-416-05

Current NADAC: $0.10041 per EA · Effective Sep 23, 2026 · Est. package price $50.21 (500 EA)

Current Package Pricing Information

The current wholesale acquisition cost for Bupropion Hydrochloride Xl (NDC 42806-416-05) is $0.10041 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Sep 23, 2026.

As a a human prescription drug provided by Epic Pharma, Llc, this medication is distributed in a 500 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.10041
Per EA

Effective Date
Sep 23, 2026
Billable Units
500 EA
Estimated Package Price
$50.21
Data Status
As of Oct 07, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
500 TABLET, EXTENDED RELEASE in 1 BOTTLE, PLASTIC
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jun 2023, the NADAC wholesale price for (NDC ) has moved within a range of $0.10041 to $0.19885 per EA. Over this 3 years and 3 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.1004 - $0.1989
Market Volatility
98.04% Variance
Latest Trend
0.95%

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Sep 23, 2026 $0.10041 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 23, 2026 $0.10041 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 23, 2026 $0.10041 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 19, 2026 $0.10137 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 19, 2026 $0.10137 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 19, 2026 $0.10137 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 22, 2026 $0.10412 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 22, 2026 $0.10412 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 22, 2026 $0.10412 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 17, 2026 $0.11150 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 17, 2026 $0.11150 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 17, 2026 $0.11150 EAC/I - Chain or Independent PharmacyCode 1G - Generic

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: October 07, 2026