Aptensio Xr
Pricing Report NDC 42858-404-45

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

This product is EXCLUDED from the official NDC directory because the listing data was discontinued by the firm.

The latest wholesale acquisition cost for Aptensio Xr (NDC 42858-404-45) is $8.03148 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Oct 22, 2025.

As a provided by Rhodes Pharmaceuticals Llc, this medication is distributed in a 90 CAPSULE, EXTENDED RELEASE in 1 BOTTLE, PLASTIC configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$8.03148
Per EA

Pricing Unit
Per EA Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Oct 22, 2025
Billable Units
90 EA
Estimated Package Price
$722.83
Data Status
As of Jul 08, 2026
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
B - Brand
Package NDC
42858-404-45
Description
90 CAPSULE, EXTENDED RELEASE in 1 BOTTLE, PLASTIC
Pricing Methodology Explanation
The NADAC was carried forward from the previous file.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jun 2018, the NADAC wholesale price for (NDC ) has moved within a range of $7.49432 to $8.03148 per EA. Over this 7 years and 4 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$7.4943 - $8.0315
Market Volatility
7.17% Variance
Latest Trend
0.27%
Date Unit Price Unit Source Method Rate
Oct 22, 2025 $8.03148 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Oct 22, 2025 $8.03148 EAC/I - Chain or Independent PharmacyCode 4B - Brand
Oct 22, 2025 $8.03148 EAC/I - Chain or Independent PharmacyCode 4B - Brand
Sep 17, 2025 $8.00962 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Aug 20, 2025 $8.00962 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jul 23, 2025 $8.00962 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jun 18, 2025 $8.00962 EAC/I - Chain or Independent PharmacyCode 1B - Brand
May 21, 2025 $8.01102 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Apr 23, 2025 $8.00899 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Mar 19, 2025 $8.00843 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Feb 19, 2025 $8.00798 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jan 22, 2025 $8.00119 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Dec 18, 2024 $8.00472 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Nov 20, 2024 $8.01328 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Oct 23, 2024 $7.97843 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Sep 18, 2024 $8.01084 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Aug 21, 2024 $8.01010 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jul 17, 2024 $8.01010 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jul 17, 2024 $8.01010 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jun 19, 2024 $8.00191 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jun 19, 2024 $8.00191 EAC/I - Chain or Independent PharmacyCode 1B - Brand
May 22, 2024 $7.98903 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Apr 17, 2024 $7.99468 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Apr 22, 2020 $7.97355 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Apr 22, 2020 $7.97355 EAC/I - Chain or Independent PharmacyCode 2B - Brand
Apr 22, 2020 $7.97355 EAC/I - Chain or Independent PharmacyCode 4B - Brand
Aug 01, 2019 $8.01093 EAC/I - Chain or Independent PharmacyCode 2B - Brand
Aug 01, 2019 $8.01093 EAC/I - Chain or Independent PharmacyCode 3B - Brand
Aug 01, 2019 $8.01093 EAC/I - Chain or Independent PharmacyCode 4B - Brand
Jul 17, 2019 $7.55748 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jun 20, 2018 $7.49432 EAC/I - Chain or Independent PharmacyCode 2B - Brand
Jun 20, 2018 $7.49432 EAC/I - Chain or Independent PharmacyCode 3B - Brand
Jun 20, 2018 $7.49432 EAC/I - Chain or Independent PharmacyCode 4B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026