Buprenorphine Patch
Pricing Report NDC 42858-586-40

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Buprenorphine (NDC 42858-586-40) is $45.91397 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Rhodes Pharmaceuticals Llc, this medication is distributed in a 4 POUCH in 1 CARTON / 1 PATCH in 1 POUCH / 168 h in 1 PATCH configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$45.91397
Per EA

Effective Date
Jun 17, 2026
Billable Units
1 EA
Estimated Package Price
$45.91
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
4 POUCH in 1 CARTON / 1 PATCH in 1 POUCH / 168 h in 1 PATCH
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Sep 2017, the NADAC wholesale price for (NDC ) has moved within a range of $33.15722 to $111.25375 per EA. Over this 8 years and 9 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$33.1572 - $111.2538
Market Volatility
235.53% Variance
Latest Trend
2.34%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $45.91397 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 20, 2026 $44.86244 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 22, 2026 $44.15102 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 18, 2026 $47.56824 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 18, 2026 $49.83408 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 21, 2026 $49.52994 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 17, 2025 $46.42659 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 19, 2025 $45.67862 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 22, 2025 $48.53820 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 17, 2025 $50.46872 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 20, 2025 $50.78757 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 23, 2025 $50.80173 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 18, 2025 $50.23454 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 21, 2025 $53.54979 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 23, 2025 $53.72307 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 19, 2025 $58.16033 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 19, 2025 $51.75184 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 22, 2025 $47.82747 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 18, 2024 $48.42426 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 20, 2024 $40.56364 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 23, 2024 $62.83010 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 18, 2024 $54.49821 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 21, 2024 $53.79827 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 17, 2024 $33.15722 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 19, 2024 $48.69233 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 22, 2024 $45.72202 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 17, 2024 $40.37201 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 20, 2024 $61.18886 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 21, 2024 $61.21061 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 17, 2024 $64.25686 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 20, 2023 $65.57138 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 22, 2023 $66.96173 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 18, 2023 $68.39636 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 20, 2023 $66.23571 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 23, 2023 $95.22033 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 19, 2023 $72.50659 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 21, 2023 $71.64898 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 17, 2023 $61.55764 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 19, 2023 $59.92296 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 22, 2023 $63.11579 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 22, 2023 $71.41090 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 18, 2023 $79.89778 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 21, 2022 $66.86469 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 23, 2022 $72.32040 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 19, 2022 $73.41190 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 21, 2022 $71.76786 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 17, 2022 $82.78674 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 20, 2022 $91.30673 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 22, 2022 $87.66228 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 18, 2022 $91.91671 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 20, 2022 $95.09015 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 23, 2022 $99.06250 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 23, 2022 $95.22298 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 19, 2022 $98.15476 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 22, 2021 $93.89094 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 17, 2021 $107.66567 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 20, 2021 $103.01933 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 22, 2021 $101.36941 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 18, 2021 $107.79941 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 21, 2021 $99.36083 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 23, 2021 $100.28982 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 19, 2021 $93.99917 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 21, 2021 $106.00857 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 17, 2021 $93.65405 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 17, 2021 $102.13348 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 20, 2021 $102.24278 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 23, 2020 $102.92304 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 18, 2020 $101.66944 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 21, 2020 $104.70844 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 23, 2020 $104.28109 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 19, 2020 $106.85118 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 22, 2020 $97.59109 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 17, 2020 $100.40625 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 20, 2020 $111.25375 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 22, 2020 $104.06750 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 19, 2018 $98.38250 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 22, 2018 $102.54417 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 20, 2018 $101.50750 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 20, 2018 $101.50750 EAC/I - Chain or Independent PharmacyCode 4, 6G - Generic
Apr 18, 2018 $101.42350 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 18, 2018 $101.42350 EAC/I - Chain or Independent PharmacyCode 4, 6G - Generic
Oct 18, 2017 $98.58167 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 18, 2017 $98.58167 EAC/I - Chain or Independent PharmacyCode 4, 6G - Generic
Sep 13, 2017 $99.39600 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 13, 2017 $99.39600 EAC/I - Chain or Independent PharmacyCode 4, 6G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026