Rebif Injection, Solution
Pricing Report NDC 44087-0044-3
Current Package Pricing Information
The latest wholesale acquisition cost for Rebif (NDC 44087-0044-3) is $1849.88373 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jan 03, 2026.
As a a human prescription drug provided by Emd Serono, Inc., this medication is distributed in a 12 SYRINGE, GLASS in 1 CARTON / .5 mL in 1 SYRINGE, GLASS (44087-0044-9) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.
NADAC Pricing Summary
NADAC pricing snapshot for this package NDC
Acquisition Cost $1,849.88373 Per ML
The NADAC was calculated based on package size.
Historical Pricing Trends & Acquisition Cost Benchmarks
Since Aug 2013, the NADAC wholesale price for (NDC ) has moved within a range of $735.48871 to $1,849.88373 per ML. Over this 12 years and 5 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.
$735.4887 - $1,849.8837
151.52% Variance
4.00%
Recent NADAC Price History
| Date | Unit Price | Unit | Source | Method | Rate |
|---|---|---|---|---|---|
| Jan 03, 2026 | $1849.88373 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 03, 2026 | $1849.88373 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 29, 2025 | $1778.73436 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 29, 2025 | $1778.73436 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 29, 2025 | $1778.73436 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 22, 2025 | $1710.32150 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Dec 18, 2024 | $1709.58778 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 20, 2024 | $1708.67062 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Oct 23, 2024 | $1706.78200 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jan 15, 2021 | $1441.53862 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 15, 2021 | $1441.53862 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Apr 03, 2020 | $1359.94209 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
Earlier NADAC Price History
| Date | Unit Price | Unit | Source | Method | Rate |
|---|---|---|---|---|---|
| Apr 03, 2020 | $1359.94209 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Sep 26, 2019 | $1295.18294 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Sep 26, 2019 | $1295.18294 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 11, 2019 | $1235.86159 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 11, 2019 | $1235.86159 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jul 18, 2018 | $1182.64267 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jul 18, 2018 | $1182.64267 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jul 18, 2018 | $1182.64267 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Feb 01, 2018 | $1164.09900 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Feb 01, 2018 | $1164.09900 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Aug 02, 2017 | $1099.24362 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Aug 02, 2017 | $1099.24362 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Aug 02, 2017 | $1099.24362 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jun 21, 2017 | $1060.02278 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jun 21, 2017 | $1060.02278 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Feb 22, 2017 | $1051.31981 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Feb 22, 2017 | $1051.31981 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Feb 22, 2017 | $1051.31981 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 06, 2017 | $1064.40016 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jul 01, 2016 | $1008.91010 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jul 01, 2016 | $1008.91010 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jul 01, 2016 | $1008.91010 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 12, 2016 | $960.86676 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 12, 2016 | $960.86676 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 12, 2016 | $960.86676 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Sep 04, 2015 | $924.79958 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Sep 04, 2015 | $924.79958 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Feb 20, 2015 | $872.45243 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Feb 20, 2015 | $872.45243 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Feb 20, 2015 | $872.45243 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Oct 03, 2014 | $830.90708 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Oct 03, 2014 | $830.90708 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Oct 03, 2014 | $830.90708 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Feb 19, 2014 | $776.54867 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Feb 19, 2014 | $776.54867 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Dec 21, 2013 | $786.97292 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Dec 21, 2013 | $786.97292 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Aug 01, 2013 | $735.48871 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Aug 01, 2013 | $735.48871 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
Pricing Methodology Legend
- Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
- Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
- Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
- Code 4: The NADAC was carried forward from the previous file.
- Code 5: The NADAC was calculated based on package size.
Understanding NADAC Pricing Data
The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.
Important Price Distinction:
The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.
NADAC Pricing Data Last Updated on: October 07, 2026
