Rebif Injection, Solution
Pricing Report NDC 44087-0044-3

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The latest wholesale acquisition cost for Rebif (NDC 44087-0044-3) is $1849.88373 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jan 03, 2026.

As a a human prescription drug provided by Emd Serono, Inc., this medication is distributed in a 12 SYRINGE, GLASS in 1 CARTON / .5 mL in 1 SYRINGE, GLASS (44087-0044-9) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$1,849.88373
Per ML

Effective Date
Jan 03, 2026
Data Status
As of Mar 11, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
12 SYRINGE, GLASS in 1 CARTON / .5 mL in 1 SYRINGE, GLASS (44087-0044-9)
Pricing Methodology Explanation
The NADAC was carried forward from the previous file.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Aug 2013, the NADAC wholesale price for (NDC ) has moved within a range of $735.48871 to $1,849.88373 per ML. Over this 12 years and 5 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$735.4887 - $1,849.8837
Market Volatility
151.52% Variance
Latest Trend
4.00%
Date Unit Price Unit Source Method Rate
Jan 03, 2026 $1849.88373 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 03, 2026 $1849.88373 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 29, 2025 $1778.73436 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 29, 2025 $1778.73436 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 29, 2025 $1778.73436 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 22, 2025 $1710.32150 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Dec 18, 2024 $1709.58778 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 20, 2024 $1708.67062 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 23, 2024 $1706.78200 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 15, 2021 $1441.53862 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 15, 2021 $1441.53862 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Apr 03, 2020 $1359.94209 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Apr 03, 2020 $1359.94209 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Sep 26, 2019 $1295.18294 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Sep 26, 2019 $1295.18294 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 11, 2019 $1235.86159 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 11, 2019 $1235.86159 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jul 18, 2018 $1182.64267 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 18, 2018 $1182.64267 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 18, 2018 $1182.64267 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Feb 01, 2018 $1164.09900 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Feb 01, 2018 $1164.09900 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 02, 2017 $1099.24362 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 02, 2017 $1099.24362 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Aug 02, 2017 $1099.24362 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jun 21, 2017 $1060.02278 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 21, 2017 $1060.02278 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Feb 22, 2017 $1051.31981 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Feb 22, 2017 $1051.31981 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Feb 22, 2017 $1051.31981 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 06, 2017 $1064.40016 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 01, 2016 $1008.91010 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2016 $1008.91010 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 01, 2016 $1008.91010 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 12, 2016 $960.86676 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 12, 2016 $960.86676 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 12, 2016 $960.86676 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Sep 04, 2015 $924.79958 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Sep 04, 2015 $924.79958 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Feb 20, 2015 $872.45243 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Feb 20, 2015 $872.45243 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Feb 20, 2015 $872.45243 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Oct 03, 2014 $830.90708 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Oct 03, 2014 $830.90708 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Oct 03, 2014 $830.90708 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Feb 19, 2014 $776.54867 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Feb 19, 2014 $776.54867 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Dec 21, 2013 $786.97292 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Dec 21, 2013 $786.97292 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Aug 01, 2013 $735.48871 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 01, 2013 $735.48871 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026