Avaclyr Ointment
NDC Package 48102-028-35

11-digit billing NDC: 48102002835
Table of Contents
    1. Package Information
    2. Frequently Asked Questions

Package Information

Avaclyr (acyclovir) ointment is aVACLYR is a sterile topical antiviral indicated for the treatment of acute herpetic keratitis (dendritic ulcers) in patients with herpes simplex (HSV-1 and HSV-2) virus. This formulation utilizes a ointment delivery system. Marketed by Fera Pharmaceuticals, Llc, this product is identified by NDC 48102-028 and is authorized under FDA application NDA202408.

Identification & Billing

NDC Package Code
48102-028-35
Package Description
1 TUBE in 1 CARTON / 3.5 g in 1 TUBE
Product Code
48102-028
11-Digit Billing Format
48102002835
RxNorm Crosswalk

Clinical Specifications

Proprietary Name
Avaclyr
Non-Proprietary Name
Acyclovir
Substance Name
Acyclovir
Dosage Form
Ointment - A semisolid3 dosage form, usually containing <20% water and volatiles5 and >50% hydrocarbons, waxes, or polyols as the vehicle. This dosage form is generally for external application to the skin or mucous membranes.
Administration Route
Ophthalmic - Administration to the external eye.
Active Ingredient(s)
ACYCLOVIR 30 mg/g
Pharmacologic Class
Usage Information
AVACLYR is a sterile topical antiviral indicated for the treatment of acute herpetic keratitis (dendritic ulcers) in patients with herpes simplex (HSV-1 and HSV-2) virus.

Regulatory & Marketing

Labeler Name
Fera Pharmaceuticals, Llc
Product Type
Human Prescription Drug
FDA Application #
NDA202408
Marketing Category
NDA - A product marketed under an approved New Drug Application.
Start Marketing Date
01-31-2026
Listing Expiration
12-31-2027
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 48102-028-35 identifies a specific commercial package of 1 tube in 1 carton / 3.5 g in 1 tube of Avaclyr, a human prescription drug labeled by Fera Pharmaceuticals, Llc. This ointment is formulated for ophthalmic use and contains acyclovir as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Fera Pharmaceuticals, Llc on January 31, 2026. The current certification is valid through December 31, 2027.

How is this Fera Pharmaceuticals, Llc product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 48102002835. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (5-3-2)
48102-028-35
11-Digit CMS (5-4-2)
48102-0028-35

Note: The zero is added to the Product segment to maintain the 5-4-2 structure.