Strong Iodine Solution Solution/ Drops
NDC Package 48433-230-15

View Billable Units, 11-Digit Conversion Format, and RxNorm mappings
Table of Contents
    1. Package Information
    2. Frequently Asked Questions

Package Information

Strong Iodine Solution solution/ dropses is strong Iodine Solution, containing 5 percent of iodine and 10 percent of potassium iodide, is employed in the prophylaxis of simple and colloid goiters and in the treatment of exophthalmic goiter.  It can be used alone as a preoperative preparation but is now most commonly used concomitantly with propylthiouracil and other antithyroid drugs.  When used with these drugs, Strong Iodine Solution produces involution of the hyperplastic gland thus making a less triable and vascular gland for thyroidectomy.  In addition, it has an additive antithyroid action that helps make the patient enthyroid faster than if the antithyroid drugs were used alone. This formulation utilizes a solution/ drops delivery system. Marketed by Safecor Health, Llc, this product is identified by NDC 48433-230.

Identification & Billing

NDC Package Code
48433-230-15
Package Description
14 mL in 1 BOTTLE
Product Code
48433-230
11-Digit Billing Format
48433023015
Billing Unit
ML - Billing unit of "milliliter" is used when a product is measured by its liquid volume.
Units Per Package
14 ML
RxNorm Crosswalk
  • RxCUI: 204913 - strong iodine (iodine 5 % / potassium iodide 10 % ) Oral Solution
  • RxCUI: 204913 - iodine 50 MG/ML / potassium iodide 100 MG/ML Oral Solution
  • RxCUI: 204913 - Iodine 50 MG/ML / K+ Iodide 100 MG/ML Oral Solution
  • RxCUI: 204913 - Iodine 50 MG/ML / Pot Iodide 100 MG/ML Oral Solution

Clinical Specifications

Proprietary Name
Strong Iodine Solution
Non-Proprietary Name
Strong Iodine Solution
Substance Name
Iodine; Potassium Iodide
Dosage Form
Solution/ Drops - A solution which is usually administered in a drop-wise fashion.
Administration Route
Oral - Administration to or by way of the mouth.
Active Ingredient(s)
Usage Information
Strong Iodine Solution, containing 5 percent of iodine and 10 percent of potassium iodide, is employed in the prophylaxis of simple and colloid goiters and in the treatment of exophthalmic goiter.  It can be used alone as a preoperative preparation but is now most commonly used concomitantly with propylthiouracil and other antithyroid drugs.  When used with these drugs, Strong Iodine Solution produces involution of the hyperplastic gland thus making a less triable and vascular gland for thyroidectomy.  In addition, it has an additive antithyroid action that helps make the patient enthyroid faster than if the antithyroid drugs were used alone.

Regulatory & Marketing

Labeler Name
Safecor Health, Llc
Product Type
Human Prescription Drug
Marketing Category
UNAPPROVED DRUG OTHER - An unapproved drug product in a marketing category that is not reflected on a particular list.
Start Marketing Date
09-20-2008
Listing Expiration
12-31-2026
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 48433-230-15 identifies a specific commercial package of 14 ml in 1 bottle of Strong Iodine Solution, a human prescription drug labeled by Safecor Health, Llc. This product is billed per "ML" milliliter and contains an estimated amount of 14 billable units per package. This solution/ drops is formulated for oral use and contains iodine; potassium iodide as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Safecor Health, Llc on September 20, 2008. The current certification is valid through December 31, 2026.

How is this Safecor Health, Llc product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 48433023015. Quantities are measured in per "ml or milliliter", products billed per milliliter are usually products measured by liquid volume.. There are 14 total billable units per package. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (5-3-2)
48433-230-15
11-Digit CMS (5-4-2)
48433-0230-15

Note: The zero is added to the Product segment to maintain the 5-4-2 structure.