Epinephrine Injection
Pricing Report NDC 49502-101-02

Current NADAC: $141.85384 per EA · Effective Aug 19, 2026 · Est. package price $141.85 (1 EA)

Current Package Pricing Information

The current wholesale acquisition cost for Epinephrine (NDC 49502-101-02) is $141.85384 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Aug 19, 2026.

As a a human prescription drug provided by Viatris Specialty Llc, this medication is distributed in a 2 CONTAINER in 1 CARTON / 1 SYRINGE, GLASS in 1 CONTAINER (49502-101-01) / .3 mL in 1 SYRINGE, GLASS configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$141.85384
Per EA

Effective Date
Aug 19, 2026
Billable Units
1 EA
Estimated Package Price
$141.85
Data Status
As of Sep 09, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
2 CONTAINER in 1 CARTON / 1 SYRINGE, GLASS in 1 CONTAINER (49502-101-01) / .3 mL in 1 SYRINGE, GLASS
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Mar 2017, the NADAC wholesale price for (NDC ) has moved within a range of $139.80471 to $145.12923 per EA. Over this 9 years and 5 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$139.8047 - $145.1292
Market Volatility
3.81% Variance
Latest Trend
0.21%

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Aug 19, 2026 $141.85384 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 22, 2026 $142.14759 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 17, 2026 $142.84098 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 20, 2026 $142.93970 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 22, 2026 $142.86966 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 18, 2026 $143.10789 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 18, 2026 $142.98403 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 21, 2026 $142.83382 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 17, 2025 $142.43326 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 19, 2025 $142.41369 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 22, 2025 $142.29157 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 17, 2025 $142.43737 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: September 09, 2026