Estradiol Patch
Product Images NDC 50090-7611

Product Visual Gallery

This gallery contains 12 technical images submitted to the FDA as part of the official labeling for Estradiol (NDC 50090-7611). Unlike standard consumer photos, these assets often include clinical data figures, molecular chemical structures, and official manufacturer packaging layouts.

As provided by A-s Medication Solutions, these visuals offer a comprehensive scientific overview of the product's physical and chemical identity, aiding pharmacists and researchers in product verification and study.

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Estradiol Structural Formula (Image 01)

Chemical structure of estradiol hemihydrate, showing the steroid framework with hydroxyl groups and a water molecule represented as ½ H2O.*

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Transdermal Parts (Image 02)

Diagram illustrating the four layers of an estradiol transdermal patch: foam backing with adhesive layer, polyester film, acrylate adhesive matrix containing estradiol, and protective liner.*

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Figure 1 Mean Serum 17β-estradiol Concentrations Vs. Time Profile Following Application Of A 7.75 Cm2 Transdermal Patch And Application Of A 15.5 Cm2 Estradiol Transdermal System Continuous Delivery (once-weekly) Patch (Image 03)

A pharmacokinetic graph showing estradiol concentrations (pg/mL) over time (hours) for two estradiol transdermal systems of different sizes, 7.75 cm² and 3.65 cm². The concentration curves depict absorption and decline phases over 180 hours.*

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Figure 2 Observed Mean (± S.e.) Estradiol Serum Concentrations For A One Week Application Of The Estradiol Transdermal System Continuous Delivery (once-weekly) (31 Cm2) To The Abdomen And Buttocks Of 38 Postmenopausal Women (Image 04)

A line graph depicting mean concentrations of a substance in pg/mL over time in hours after patch application, comparing two treatment sites labeled as Buttock and Abdomen. The x-axis shows sampling time from 0 to 192 hours, and the y-axis shows mean concentration from 0 to 200 pg/mL with error bars.*

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Figure 3 Mean Percent Change From Baseline In Lumbar Spine (a-p View) Bone Mineral Density By Treatment And Time Last Observation Carried Forward (Image 05)

A line graph depicting percent change over time from baseline to 24 months, comparing different treatment groups labeled as Placebo, 7.75 cm², 15.5 cm², 18.6 cm², and 31 cm². The x-axis shows treatment visit intervals (Baseline, 6 months, 12 months, 18 months, 24 months) and the y-axis shows percent change values ranging from -6% to 6%. Each treatment group is represented by distinct dashed and solid lines.*

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Figure 4 Mean Percent Change From Baseline In Total Hip By Treatment And Time Last Observation Carried Forward (Image 06)

A line graph showing percent change over time from baseline to 24 months for different treatment groups, including placebo and three patch sizes (7.75 cm², 15.5 cm², and 31 cm²). The x-axis represents visit time points (Baseline, 6 months, 12 months, 18 months, 24 months) and the y-axis shows percent change, with values ranging from -6% to 6%. Different line styles distinguish the treatment groups, demonstrating varying trends in percent change across the study duration.*

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Instructions For Use Figure A (Image 07)

Packaging label for Estradiol transdermal system, USP continuous delivery (once-weekly) patch. The label indicates it contains one system. The product is manufactured by Mylan.*

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Instructions For Use Figures B And C (Image 08)

Instructional illustrations showing removal of an estradiol transdermal system (patch) package. The first figure highlights tear notches on the sealed pouch; the second shows hands peeling open the pouch at the tear notch; the third depicts carefully removing the estradiol patch from the opened pouch. The product label on the pouch reads Estradiol Transdermal System, USP, Continuous Delivery (Once-Weekly), with the labeler name Mylan.*

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Instructions For Use Figures D And E (Image 09)

An instructional illustration showing a person holding an Estradiol transdermal patch by its edges and peeling away the protective liner. The protective liner is depicted separately with a magnified view emphasizing repeated text labeling it as 'Estradiol (Once Weekly).'}*

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Instructions For Use Figures F And G (Image 10)

An instructional illustration depicting the proper placement of an Estradiol transdermal patch. Figure F shows the patch being applied to the lower abdomen, and Figure G shows the patch applied to the buttock area, demonstrating acceptable application sites for the patch.*

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Instructions For Use Figure H (Image 11)

An instructional illustration showing a hand applying a circular transdermal patch labeled "Estradiol" to the underarm area, demonstrating correct patch placement for the Estradiol 0.05 mg/day transdermal patch by A-S Medication Solutions.*

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Label Image (Lbl500907611)

Estradiol 0.05 mg/d transdermal patch by A-S Medication Solutions, labeled for once-weekly use. The label includes dosage information, lot number, storage instructions to keep at 68 to 77 degrees F, and a note to use one patch system at a time without unsealing others. Package contains 4 transdermal systems.*

* About these descriptions: Image descriptions on this page are generated by automated AI analysis of the product label images from the manufacturer's FDA label submission (SPL). They are provided for reference only and may contain errors or omissions. Always rely on the printed label itself and the official FDA labeling, and consult a pharmacist or healthcare professional with any questions about this product.