Estradiol Patch
Product Images NDC 50090-7984

Product Visual Gallery

This gallery contains 12 technical images submitted to the FDA as part of the official labeling for Estradiol (NDC 50090-7984). Unlike standard consumer photos, these assets often include clinical data figures, molecular chemical structures, and official manufacturer packaging layouts.

As provided by A-s Medication Solutions, these visuals offer a comprehensive scientific overview of the product's physical and chemical identity, aiding pharmacists and researchers in product verification and study.

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Estradiol Structural Formula (Image 01)

Chemical structure of estradiol with a notation indicating it includes one half molecule of water (hemihydrate). The diagram shows the characteristic steroid skeleton with hydroxyl groups at specific positions.*

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Transdermal Parts (Image 02)

An instructional diagram illustrating the layered composition of an Estradiol transdermal patch. It shows the foam backing with adhesive layer, polyester film, acrylate adhesive matrix containing estradiol, and protective liner labeled in sequence.*

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Figure 1 Mean Serum 17β-estradiol Concentrations Vs. Time Profile Following Application Of A 7.75 Cm2 Transdermal Patch And Application Of A 15.5 Cm2 Estradiol Transdermal System Continuous Delivery (once-weekly) Patch (Image 03)

A line graph showing estradiol concentrations (pg/mL) over time (hours) for two sizes of estradiol transdermal systems. The curves represent the 7.75 cm² and 4.625 cm² patches, with concentration measurements peaking around 20 to 30 hours and declining over a 180-hour period.*

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Figure 2 Observed Mean (± S.e.) Estradiol Serum Concentrations For A One Week Application Of The Estradiol Transdermal System Continuous Delivery (once-weekly) (31 Cm2) To The Abdomen And Buttocks Of 38 Postmenopausal Women (Image 04)

A line graph showing mean concentration (pg/mL) over time (hours) after application of an estradiol transdermal patch. Two treatment groups, labeled "Buttock" and "Abdomen," are plotted with error bars, depicting pharmacokinetic profiles up to 192 hours post-application.*

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Figure 3 Mean Percent Change From Baseline In Lumbar Spine (a-p View) Bone Mineral Density By Treatment And Time Last Observation Carried Forward (Image 05)

A line graph showing percentage change over time from baseline to 24 months, comparing different treatment groups including placebo and estradiol patches of various sizes (7.75 cm², 15.5 cm², 18.6 cm², and 31 cm²). Percent change is plotted on the vertical axis, with treatment visits on the horizontal axis.*

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Figure 4 Mean Percent Change From Baseline In Total Hip By Treatment And Time Last Observation Carried Forward (Image 06)

A line graph showing percent change over time from baseline across visits (6, 12, 18, and 24 months) for a treatment study. The graph compares placebo and different patch sizes (7.75 cm², 15.5 cm², 18.6 cm², and 31 cm²) as indicated in the legend. The y-axis represents percent change; the x-axis denotes visit time points.*

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Instructions For Use Figure A (Image 07)

Estradiol transdermal patch label showing a continuous delivery system for once-weekly use. The label indicates the packaging contains one system and includes the Mylan logo. No strength or additional dosage details are visible on the label.*

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Instructions For Use Figures B And C (Image 08)

Illustrations showing the removal process of an Estradiol transdermal system (patch) labeled for continuous delivery (once-weekly). Figure B details the patch packaging with tear notches for opening. Another illustration shows hands tearing open the pouch, and Figure C shows careful removal of the estradiol patch from its packaging.*

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Instructions For Use Figures D And E (Image 09)

An instructional illustration showing how to handle an Estradiol transdermal patch. Figure D highlights the protective liner on the patch, and Figure E depicts hands peeling off the protective liner from the patch before application.*

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Instructions For Use Figures F And G (Image 10)

Illustration showing application of an Estradiol transdermal patch on the lower abdomen (Figure F) and the buttock (Figure G) areas of the body. Both figures depict a hand pressing the patch onto the skin surface for adhesion.*

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Instructions For Use Figure H (Image 11)

An illustration labeled Figure H showing a hand applying an estradiol transdermal patch to the skin of the upper arm. The patch is round and labeled with dosage and other text. The image demonstrates the proper application site for the estradiol patch.*

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Label Image (Lbl500907984)

Estradiol 0.1 mg/day transdermal system patch by A-S Medication Solutions. The packaging indicates a once-weekly dosing, covering 31 cm² system area, delivering 0.1 mg estradiol daily. The label includes storage instructions to keep at 68 to 77 degrees Fahrenheit, cautions to not store unpunched patches, and specifies a quantity of 4 transdermal systems per pack.*

* About these descriptions: Image descriptions on this page are generated by automated AI analysis of the product label images from the manufacturer's FDA label submission (SPL). They are provided for reference only and may contain errors or omissions. Always rely on the printed label itself and the official FDA labeling, and consult a pharmacist or healthcare professional with any questions about this product.