Estradiol Patch
Product Images NDC 50090-7986

Product Visual Gallery

This gallery contains 12 technical images submitted to the FDA as part of the official labeling for Estradiol (NDC 50090-7986). Unlike standard consumer photos, these assets often include clinical data figures, molecular chemical structures, and official manufacturer packaging layouts.

As provided by A-s Medication Solutions, these visuals offer a comprehensive scientific overview of the product's physical and chemical identity, aiding pharmacists and researchers in product verification and study.

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Estradiol Structural Formula (Image 01)

Chemical structure diagram of estradiol hydrate, showing its molecular framework with hydroxyl groups and a half molecule of water (½ H2O). This illustration represents the active ingredient estradiol.*

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Transdermal Parts (Image 02)

An instructional diagram illustrating the four layers of an estradiol transdermal patch: foam backing with adhesive layer, polyester film, acrylate adhesive matrix containing estradiol, and protective liner.*

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Figure 1 Mean Serum 17β-estradiol Concentrations Vs. Time Profile Following Application Of A 7.75 Cm2 Transdermal Patch And Application Of A 15.5 Cm2 Estradiol Transdermal System Continuous Delivery (once-weekly) Patch (Image 03)

A concentration-time plot showing estradiol levels (pg/mL) over 180 hours for two estradiol transdermal systems: 7.75 cm² and 5 cm² patch sizes. The y-axis represents concentrations, and the x-axis indicates time in hours, with markers distinguishing the two transdermal system sizes.*

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Figure 2 Observed Mean (± S.e.) Estradiol Serum Concentrations For A One Week Application Of The Estradiol Transdermal System Continuous Delivery (once-weekly) (31 Cm2) To The Abdomen And Buttocks Of 38 Postmenopausal Women (Image 04)

A line graph showing mean concentration (pg/mL) over time (hours after patch application) comparing drug levels at two different sampling sites, buttock and abdomen, following administration of an estradiol patch. The x-axis represents sampling time from 0 to 192 hours, while the y-axis shows mean concentration values, peaking around 24-36 hours and then declining over time for both sites.*

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Figure 3 Mean Percent Change From Baseline In Lumbar Spine (a-p View) Bone Mineral Density By Treatment And Time Last Observation Carried Forward (Image 05)

A line graph showing percent change over time from baseline to 24 months. The graph compares four treatment groups with different patch sizes (7.75 cm², 15.5 cm², 18.6 cm², and 31 cm²) and a placebo group. The x-axis represents visit times from baseline to 24 months, and the y-axis represents percent change. Treatment groups show varying positive percent changes, while the placebo group shows a negative percent change over time.*

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Figure 4 Mean Percent Change From Baseline In Total Hip By Treatment And Time Last Observation Carried Forward (Image 06)

A line graph showing percent change over time from baseline to 24 months. The x-axis is labeled with treatment visits (baseline, 6 months, 12 months, 18 months, 24 months), and the y-axis represents percent change. The graph compares placebo and three different treatment sizes (7.75 cm², 15.5 cm², and 31 cm²) with lines indicating trends across time points.*

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Instructions For Use Figure A (Image 07)

Estradiol transdermal system patch packaging label showing the brand name Estradiol, described as a transdermal system with continuous delivery once weekly. The label indicates contents of 1 system and includes the manufacturer name Mylan. The image depicts the front label of the patch pouch.*

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Instructions For Use Figures B And C (Image 08)

Illustrations showing how to open and apply the Estradiol transdermal patch packaging. Figure B highlights tear notches on the pouch for easy opening. Figure C shows careful removal of the Estradiol patch from its packaging. The patch is a continuous delivery system labeled for once-weekly use by Mylan.*

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Instructions For Use Figures D And E (Image 09)

Illustration showing hands peeling the protective liner from an Estradiol transdermal patch. A close-up inset details the patch surface labeled "Estradiol (Once Weekly)." The protective liner is clearly marked and being removed to expose the adhesive patch.*

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Instructions For Use Figures F And G (Image 10)

Instructional illustration showing the application of the Estradiol 0.075 mg/d transdermal patch on the lower abdomen (Figure F) and upper buttocks (Figure G) areas of the body. The diagrams demonstrate proper patch placement for transdermal delivery.*

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Instructions For Use Figure H (Image 11)

An instructional illustration labeled 'Figure H' showing a hand applying or holding a circular transdermal patch on the skin, consistent with the administration of Estradiol 0.075 mg/d transdermal patch.*

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Label Image (Lbl500907986)

Estradiol 0.075 mg/day transdermal system patch carton from A-S Medication Solutions, with a stated dosing of one patch weekly. The label includes NDC 50090-7986-0, lot number, storage instructions to store between 68 to 77 degrees Fahrenheit, and to keep patches unopened until use. Package contains four transdermal systems.*

* About these descriptions: Image descriptions on this page are generated by automated AI analysis of the product label images from the manufacturer's FDA label submission (SPL). They are provided for reference only and may contain errors or omissions. Always rely on the printed label itself and the official FDA labeling, and consult a pharmacist or healthcare professional with any questions about this product.