Estradiol Patch
Product Images NDC 50090-7988

Product Visual Gallery

This gallery contains 12 technical images submitted to the FDA as part of the official labeling for Estradiol (NDC 50090-7988). Unlike standard consumer photos, these assets often include clinical data figures, molecular chemical structures, and official manufacturer packaging layouts.

As provided by A-s Medication Solutions, these visuals offer a comprehensive scientific overview of the product's physical and chemical identity, aiding pharmacists and researchers in product verification and study.

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Estradiol Structural Formula (Image 01)

Chemical structure of estradiol, showing its steroid backbone with hydroxyl groups and a water molecule component (½ H2O).*

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Transdermal Parts (Image 02)

An illustration diagram showing the layered construction of the Estradiol transdermal patch. The diagram labels four layers from top to bottom: foam backing with adhesive layer, polyester film, acrylate adhesive matrix containing estradiol, and protective liner.*

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Figure 1 Mean Serum 17β-estradiol Concentrations Vs. Time Profile Following Application Of A 7.75 Cm2 Transdermal Patch And Application Of A 15.5 Cm2 Estradiol Transdermal System Continuous Delivery (once-weekly) Patch (Image 03)

A line graph showing estradiol concentrations (pg/mL) measured over time (hours) up to 180 hours. Two curves represent different sizes of estradiol transdermal systems (7.75 cm² and 5 cm²) with concentration values peaking around 24-36 hours and gradually decreasing thereafter.*

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Figure 2 Observed Mean (± S.e.) Estradiol Serum Concentrations For A One Week Application Of The Estradiol Transdermal System Continuous Delivery (once-weekly) (31 Cm2) To The Abdomen And Buttocks Of 38 Postmenopausal Women (Image 04)

A line graph showing mean estradiol concentration (pg/mL) over time in hours after application of a 0.06 mg/d estradiol transdermal patch. Two lines compare concentrations at two sampling sites: buttock and abdomen, with timepoints extending up to 192 hours.*

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Figure 3 Mean Percent Change From Baseline In Lumbar Spine (a-p View) Bone Mineral Density By Treatment And Time Last Observation Carried Forward (Image 05)

A line graph illustrating percentage change over time from baseline to 24 months across different treatment groups with varying patch sizes (7.75 cm², 15.5 cm², 18.6 cm², 31 cm²) and placebo. The x-axis represents visit time points (baseline, 6 months, 12 months, 18 months, 24 months), and the y-axis shows percentage change, with separate trend lines for each treatment group.*

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Figure 4 Mean Percent Change From Baseline In Total Hip By Treatment And Time Last Observation Carried Forward (Image 06)

A line graph showing percentage change over time in a treatment study, with the x-axis labeled with baseline and visits at 6, 12, 18, and 24 months, and the y-axis representing percentage change. The graph includes data lines for placebo and Estradiol patch sizes of 7.75 cm², 15.5 cm², 18.6 cm², and 31 cm².*

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Instructions For Use Figure A (Image 07)

Estradiol transdermal system USP in a patch dosage form for continuous once-weekly delivery. The label indicates it contains one system and is manufactured by Mylan. The product is a human prescription drug for transdermal use.*

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Instructions For Use Figures B And C (Image 08)

An instructional illustration showing removal of an Estradiol transdermal system (patch). Figure B highlights tear notches on the packaging for easy opening, and Figure C depicts hands carefully removing the circular Estradiol patch from its protective pouch. The packaging is labeled with Estradiol, indicating continuous delivery once weekly, and displays the Mylan logo.*

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Instructions For Use Figures D And E (Image 09)

Illustration showing a person peeling the protective liner from an Estradiol patch, highlighting the patch itself and the liner labeled with "Estradiol (Once Weekly)" text. The diagram visually explains the removal process of the protective liner from the transdermal patch.*

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Instructions For Use Figures F And G (Image 10)

Illustration showing the application of a transdermal patch, specifically Estradiol 0.06 mg/d, with Figure F demonstrating placement on the lower abdomen and Figure G demonstrating placement on the buttocks.*

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Instructions For Use Figure H (Image 11)

An instructional illustration labeled Figure H showing a hand applying a transdermal patch labeled Estradiol to the skin area near the lower abdomen or hip. The patch is circular and appears to have printed text on it.*

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Label Image (Lbl500907988)

Estradiol 0.06 mg/day transdermal patch by A-S Medication Solutions, delivered once weekly. The label includes storage instructions to keep at 68 to 77 degrees F and to avoid storing unopened patches for over 60 days. The package contains four transdermal systems. The NDC is 50090-7988-0.*

* About these descriptions: Image descriptions on this page are generated by automated AI analysis of the product label images from the manufacturer's FDA label submission (SPL). They are provided for reference only and may contain errors or omissions. Always rely on the printed label itself and the official FDA labeling, and consult a pharmacist or healthcare professional with any questions about this product.