Bromo Seltzer Tablet, Effervescent
NDC Package 50201-0421-2

View Billable Units, 11-Digit Conversion Format, and RxNorm mappings
Table of Contents
    1. Package Information
    2. Frequently Asked Questions

Package Information

Bromo Seltzer (aspirin, sodium bicarbonate, citric acid) tablets is ■ do not exceed recommended dosage■ to avoid serious injury, completely dissolve tablets in 4 oz. This formulation utilizes a tablet, effervescent delivery system. Marketed by Tower Laboratories Ltd, this product is identified by NDC 50201-0421 and is authorized under FDA application M013.

Identification & Billing

NDC Package Code
50201-0421-2
Package Description
10 POUCH in 1 CARTON / 2 TABLET, EFFERVESCENT in 1 POUCH
Product Code
50201-0421
11-Digit Billing Format
50201042102
RxNorm Crosswalk
  • RxCUI: 1536675 - aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet
  • RxCUI: 1536675 - ASA 325 MG / Citric Acid 1000 MG / NaHCO3 1916 MG Effervescent Oral Tablet
  • RxCUI: 1537012 - BROMO SELTZER Antacid Pain Reliever 325 MG / 1000 MG / 1916 MG Effervescent Oral Tablet
  • RxCUI: 1537012 - aspirin 325 MG / citric acid 1000 MG / sodium bicarbonate 1916 MG Effervescent Oral Tablet [Bromo Seltzer Antacid Pain Reliever]
  • RxCUI: 1537012 - ASA 325 MG / Citric Acid 1000 MG / NaHCO3 1916 MG Effervescent Oral Tablet [Bromo Seltzer Antacid Pain Reliever]

Clinical Specifications

Proprietary Name
Bromo Seltzer
Non-Proprietary Name
Aspirin, Sodium Bicarbonate, Citric Acid
Substance Name
Anhydrous Citric Acid; Aspirin; Sodium Bicarbonate
Dosage Form
Tablet, Effervescent - A solid dosage form containing mixtures of acids (e.g., citric acid, tartaric acid) and sodium bicarbonate, which release carbon dioxide when dissolved in water; it is intended to be dissolved or dispersed in water before administration.
Administration Route
Oral - Administration to or by way of the mouth.
Active Ingredient(s)
Pharmacologic Class
Usage Information
■ do not exceed recommended dosage■ to avoid serious injury, completely dissolve tablets in 4 oz. of water before taking■ adults and children 12 years and over (up to 60 years of age): 2 tablets every 4 hours - do not exceed 8 tablets in 24 hrs■ 60 years and over: 2 tablets every 4 hours - do not exceed 4 tablets in 24 hrs

Regulatory & Marketing

Labeler Name
Tower Laboratories Ltd
Product Type
Human Otc Drug
FDA Application #
M013
Marketing Category
OTC MONOGRAPH DRUG -
Start Marketing Date
07-16-2012
Listing Expiration
12-31-2026
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 50201-0421-2 identifies a specific commercial package of 10 pouch in 1 carton / 2 tablet, effervescent in 1 pouch of Bromo Seltzer, a human over the counter drug labeled by Tower Laboratories Ltd. This tablet, effervescent is formulated for oral use and contains anhydrous citric acid; aspirin; sodium bicarbonate as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Tower Laboratories Ltd on July 16, 2012. The current certification is valid through December 31, 2026.

How is this Tower Laboratories Ltd product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 50201042102. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (5-4-1)
50201-0421-2
11-Digit CMS (5-4-2)
50201-0421-02

Note: The zero is added to the Package segment to maintain the 5-4-2 structure.