Climara Patch
Product Images NDC 50419-453

Product Visual Gallery

This gallery contains 20 technical images submitted to the FDA as part of the official labeling for Climara (NDC 50419-453). Unlike standard consumer photos, these assets often include clinical data figures, molecular chemical structures, and official manufacturer packaging layouts.

As provided by Bayer Healthcare Pharmaceuticals Inc., these visuals offer a comprehensive scientific overview of the product's physical and chemical identity, aiding pharmacists and researchers in product verification and study.

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Chemical Structure (Climara 01)

Chemical structure of estradiol, the active ingredient in Climara patch. The diagram shows the molecular framework including hydroxyl groups and cycloalkane rings characteristic of this steroid hormone.*

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Image (Climara 02)

An illustration diagram showing a cross-section of the Climara estradiol transdermal patch, labeling its three layers: (1) Film backing, (2) Drug/Adhesive layer, and (3) Protective liner.*

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Figure 1 (Climara 03)

A line graph depicting the concentrations (pg/mL) of Estradiol over time (hours) following application of Climara transdermal patches of two different sizes: 6.5 cm² and 12.5 cm². The graph shows concentration levels peaking before gradually declining during a 180-hour period.*

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Figure 2 (Climara 04)

A line graph showing mean concentration (pg/mL) of estradiol over time (hours) after application of a Climara transdermal patch. Two treatment sites are compared: buttock (solid line) and abdomen (dashed line). Concentrations peak around 24-36 hours then gradually decline until 192 hours post-application.*

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Figure 3 (Climara 05)

A line chart depicting percent change over time (baseline to 24 months) for different treatment groups in a study. The x-axis shows visit times (baseline, 6, 12, 18, 24 months) and the y-axis shows percent change. Lines represent placebo and four treatments with patch sizes 6.5 cm², 12.5 cm², 15 cm², and 25 cm², illustrating trends in percent change by treatment group.*

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Figure 4 (Climara 06)

A line chart showing percentage change over time from baseline to 24 months. The graph compares treatment groups labeled placebo, 6.5 cm², 12.5 cm², and 15 cm², with percentage change tracked at 6, 12, 18, and 24 months visits. The placebo group shows a downward trend, while all treatment groups show a gradual increase.*

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Figure A (Climara 07)

Packaging label for Climara estradiol transdermal system by Bayer HealthCare Pharmaceuticals Inc. The label features the brand name Climara with the descriptor "estradiol transdermal system" along with the Bayer logo. The label indicates one transdermal system in the package.*

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Figure B (Climara 08)

An instructional illustration showing the packaging and opening method of Climara estradiol transdermal system patch. The package has a bottom tear notch and a side tear notch marked for easy opening. The image depicts hands tearing open the package at the designated tear notch.*

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Figure C (Climara 09)

An illustration showing a Climara estradiol transdermal patch with labeled parts including the Climara patch and its protective backing. The patch is octagonal, with the brand name and generic name visible on its surface.*

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Figure D (Climara 10)

Illustration showing hands removing the protective backing from a Climara estradiol transdermal patch. The image highlights the patch and the protective backing being peeled away before application.*

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Figure E (Climara 11)

An instructional illustration showing hands carefully removing a Climara estradiol transdermal patch from its packaging. The diagram emphasizes not removing the foil sticker while removing the patch.*

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Figure F (Climara 12)

Illustration showing the application of a Climara estradiol transdermal patch on the lower abdomen of a person. The diagram depicts a hand placing the patch on the skin, demonstrating the proper placement site for this hormonal therapy patch.*

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Figure G (Climara 13)

An instructional illustration showing the application of a Climara estradiol transdermal patch to the lower abdomen or hip area of a person, demonstrating proper placement on the skin.*

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Figure H (Climara 14)

An instructional illustration showing a hand applying a circular transdermal patch to the skin, demonstrating the proper placement technique for use of a medication patch such as Climara estradiol.*

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.025 Carton (Image 15)

Climara 0.025 mg/day estradiol transdermal system packaging label from Bayer HealthCare Pharmaceuticals Inc. The label features dosage strength 0.025 mg/day for 4 transdermal systems. The box displays the proprietary name Climara with the generic name estradiol transdermal system, quantity, and instructions for applying one patch per week. The design includes pink gradient accents and Bayer logos.*

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0.0375 Carton (Image 16)

Climara 0.0375 mg/day estradiol transdermal system carton label. The packaging shows four transdermal systems, each delivering 0.0375 mg/day estradiol. The label includes the Bayer HealthCare Pharmaceuticals Inc. logo and instructions for use indicating application of one transdermal system per week. The carton displays the product name, dosage strength, dosage form, and manufacturer details.*

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0.05 Carton (Image 17)

Climara 0.05 mg/day estradiol transdermal system package label for a 4-system box. The label features the Climara brand name with estradiol transdermal system text, dosage strength, and Bayer logo. It specifies the patch delivers 0.05 mg estradiol per day and includes instructions to apply one system per week. The design incorporates a pink floral graphic and blue dosage panels, indicating the transdermal route.*

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0.06 Carton (Image 18)

Climara 0.06 mg/day estradiol transdermal system packaging label. The label states it contains 4 transdermal systems, each delivering 0.06 mg/day of estradiol. It includes dosing instructions for once weekly application and manufacturer information for Bayer HealthCare Pharmaceuticals Inc. The design features a pink flower and pink wave patterns.*

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0.075 Carton (Image 19)

Climara 0.075 mg/day estradiol transdermal system carton. The label shows the product name, active ingredient, dosage strength, and delivery method as a transdermal patch. The package contains 4 systems and is manufactured by Bayer HealthCare Pharmaceuticals Inc. The label also instructs to apply one transdermal system per week for hormone therapy use.*

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0.1 Carton (Image 20)

Climara 0.1 mg/day estradiol transdermal system patch packaging label. The label shows the Bayer logo and details that each system contains 7.6 mg estradiol USP, providing 0.1 mg of estradiol per day. The package contains 4 transdermal systems and includes usage instructions and safety information.*

* About these descriptions: Image descriptions on this page are generated by automated AI analysis of the product label images from the manufacturer's FDA label submission (SPL). They are provided for reference only and may contain errors or omissions. Always rely on the printed label itself and the official FDA labeling, and consult a pharmacist or healthcare professional with any questions about this product.