Benadryl Allergy Liqui-gels Capsule, Liquid Filled
NDC Package 50580-228-48

View Billable Units, 11-Digit Conversion Format, and RxNorm mappings
Table of Contents
    1. Package Information
    2. Other Packages
    3. Frequently Asked Questions

Package Information

Benadryl Allergy Liqui-gels (diphenhydramine hydrochloride) capsules is take every 4 to 6 hoursdo not take more than 6 doses in 24 hours  adults and children 12 years and over  1 to 2 capsules  children 6 to under 12 years  1 capsule  children under 6 years  do not use this product in children under 6 years of age. This formulation utilizes a capsule, liquid filled delivery system. Marketed by Kenvue Brands Llc, this product is identified by NDC 50580-228 and is authorized under FDA application M012.

Identification & Billing

NDC Package Code
50580-228-48
Package Description
2 CARTON in 1 PACKAGE / 4 BLISTER PACK in 1 CARTON / 6 CAPSULE, LIQUID FILLED in 1 BLISTER PACK
Product Code
50580-228
11-Digit Billing Format
50580022848
RxNorm Crosswalk

Clinical Specifications

Proprietary Name
Benadryl Allergy Liqui-gels
Non-Proprietary Name
Diphenhydramine Hydrochloride
Substance Name
Diphenhydramine Hydrochloride
Dosage Form
Capsule, Liquid Filled - A solid dosage form in which the drug is enclosed within a soluble, gelatin shell which is plasticized by the addition of a polyol, such as sorbitol or glycerin, and is therefore of a somewhat thicker consistency than that of a hard shell capsule; typically, the active ingredients are dissolved or suspended in a liquid vehicle.
Administration Route
Oral - Administration to or by way of the mouth.
Active Ingredient(s)
DIPHENHYDRAMINE HYDROCHLORIDE 25 mg/1
Pharmacologic Class
Usage Information
Take every 4 to 6 hoursdo not take more than 6 doses in 24 hours  adults and children 12 years and over  1 to 2 capsules  children 6 to under 12 years  1 capsule  children under 6 years  do not use this product in children under 6 years of age

Regulatory & Marketing

Labeler Name
Kenvue Brands Llc
Product Type
Human Otc Drug
FDA Application #
M012
Marketing Category
OTC MONOGRAPH DRUG -
Start Marketing Date
03-01-2009
Listing Expiration
12-31-2027
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Other Available Packages

The following commercial packages are registered under the same Product NDC (50580-228). Click a package code to view its specific billing and regulatory data.

50580-228-24
2 BLISTER PACK in 1 CARTON / 12 CAPSULE, LIQUID FILLED in 1 BLISTER PACK
50580-228-49
3 CARTON in 1 PACKAGE / 4 BLISTER PACK in 1 CARTON / 12 CAPSULE, LIQUID FILLED in 1 BLISTER PACK

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 50580-228-48 identifies a specific commercial package of 2 carton in 1 package / 4 blister pack in 1 carton / 6 capsule, liquid filled in 1 blister pack of Benadryl Allergy Liqui-gels, a human over the counter drug labeled by Kenvue Brands Llc. This capsule, liquid filled is formulated for oral use and contains diphenhydramine hydrochloride as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Kenvue Brands Llc on March 01, 2009. The current certification is valid through December 31, 2027.

How is this Kenvue Brands Llc product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 50580022848. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (5-3-2)
50580-228-48
11-Digit CMS (5-4-2)
50580-0228-48

Note: The zero is added to the Product segment to maintain the 5-4-2 structure.