Opzelura Cream
Pricing Report NDC 50881-007-05

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Opzelura (NDC 50881-007-05) is $34.02007 per GM. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Incyte Corporation, this medication is distributed in a 1 TUBE in 1 CARTON / 60 g in 1 TUBE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$34.02007
Per GM

Effective Date
Jun 17, 2026
Billable Units
60 GM
Estimated Package Price
$2,041.20
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 TUBE in 1 CARTON / 60 g in 1 TUBE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jun 2022, the NADAC wholesale price for (NDC ) has moved within a range of $31.23580 to $34.14330 per GM. Over this 3 years and 11 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$31.2358 - $34.1433
Market Volatility
9.31% Variance
Latest Trend
No Change
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $34.02007 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 20, 2026 $34.02075 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 01, 2026 $34.14330 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2026 $34.14330 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2026 $34.14330 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 17, 2025 $33.47186 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 19, 2025 $33.47252 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 22, 2025 $33.48483 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 17, 2025 $33.48477 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 20, 2025 $33.48172 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 23, 2025 $33.47657 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 18, 2025 $33.49303 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 21, 2025 $33.53268 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 01, 2025 $33.60228 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2025 $33.60228 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2025 $33.60228 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 18, 2024 $32.81600 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 20, 2024 $32.82960 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 23, 2024 $32.84371 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 18, 2024 $32.85798 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 21, 2024 $32.87175 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 17, 2024 $32.87012 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 19, 2024 $32.87640 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 22, 2024 $32.89245 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 01, 2024 $32.75755 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2024 $32.75755 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 09, 2023 $32.16476 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 09, 2023 $32.16476 GMC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 09, 2023 $32.16476 GMC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jun 22, 2022 $31.23580 GMC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 22, 2022 $31.23580 GMC/I - Chain or Independent PharmacyCode 2, 5B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026