Product Images Procort

The text provides information for the patient on the use of topical corticosteroids, including instructions on dosage and administration, what to avoid, and the possible adverse reactions. It also warns about the potential risks of using topical corticosteroids during pregnancy and nursing, and mentions the greater susceptibility of pediatric patients to adverse reactions. The text also discusses laboratory tests that may be helpful in evaluating the suppression of the hypothalamic-pituitary-adrenal (HPA) axis caused by topical corticosteroids. The medication supplied is Hydrocortisone Acetate 1.85%, Pramoxine HCl 115% topical cream.*

ProCont® is a topical preparation containing Hydrocortisone Acetate and Pramoxine Hydrochloride, which are anti-inflammatory, anti-pruritic, and vasoconstrictive agents. Pramoxine Hydrochloride is a topical anesthetic agent that provides temporary relief from itching and pain. Topical corticosteroids are absorbed through the skin, and once absorbed, they can be handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. However, topical corticosteroids are contraindicated in patients with a history of hypersensitivity to any of the components of the preparation. Systemic absorption of topical corticosteroids can produce reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing’s syndrome, hyperglycemia, and glucosuria in some patients. Therefore, patients receiving a large dose of a potent topical steroid, applied to a large surface area and under an occlusive dressing, should be evaluated periodically for evidence of HPA axis suppression by using the urinary free cortisol and ACTH stimulation tests. If HPA axis suppression is noted, an attempt should be made to withdraw the drug or to reduce the frequency of application or to substitute a less potent steroid. Recovery of the HPA axis function is generally prompt and complete upon discontinuation of the drug.*