Trikafta Kit
RxNorm Crosswalk NDC 51167-331

View RxNorm Concepts, RxCUIs, and Term Type mappings for this NDC

RxNorm Mapping Clinical Concepts

This drug is included in the RxNorm Current Prescribable Content, a subset of RxNorm that includes all drugs available for prescription in the United States.

The product Trikafta (NDC 51167-331) is cross-mapped to the RxNorm terminology system to ensure clinical interoperability. This product is associated with 16 unique RxNorm concepts. By anchoring Vertex Pharmaceuticals Incorporated's product data to these standardized identifiers, healthcare systems can maintain accurate medication records, safely automate e-prescribing, and streamline pharmacy workflows.

The following clinical concept cards detail the semantic term types (TTY), prescribable names, and synonymous clinical strings as defined by the National Library of Medicine (NLM).

SCD
Ivacaftor 150 mg Oral Tablet
SCD
Ivacaftor 75 mg Oral Granules
SCD
Ivacaftor 75 mg Oral Tablet
SCD
Elexacaftor 100 mg / ivacaftor 75 mg / tezacaftor 50 mg Oral Tablet
GPCK
{56 (elexacaftor 100 mg / ivacaftor 75 mg / tezacaftor 50 mg Oral Tablet) / 28 (ivacaftor 150 mg Oral Tablet) } Pack
BPCK
{56 (elexacaftor 100 mg / ivacaftor 75 mg / tezacaftor 50 mg Oral Tablet) / 28 (ivacaftor 150 mg Oral Tablet) } Pack [Trikafta (100 mg / 50 mg / 75 mg; 150 mg)]
SCD
Elexacaftor 50 mg / ivacaftor 37.5 mg / tezacaftor 25 mg Oral Tablet
GPCK
{56 (elexacaftor 50 mg / ivacaftor 37.5 mg / tezacaftor 25 mg Oral Tablet) / 28 (ivacaftor 75 mg Oral Tablet) } Pack
BPCK
{56 (elexacaftor 50 mg / ivacaftor 37.5 mg / tezacaftor 25 mg Oral Tablet) / 28 (ivacaftor 75 mg Oral Tablet) } Pack [Trikafta (50 mg / 37.5 mg / 25 mg; 75 mg)]
SCD
Elexacaftor 80 mg / ivacaftor 60 mg / tezacaftor 40 mg Oral Granules
SCD
Ivacaftor 59.5 mg Oral Granules
GPCK
{28 (elexacaftor 80 mg / ivacaftor 60 mg / tezacaftor 40 mg Oral Granules) / 28 (ivacaftor 59.5 mg Oral Granules) } Pack
BPCK
{28 (elexacaftor 80 mg / ivacaftor 60 mg / tezacaftor 40 mg Oral Granules) / 28 (ivacaftor 59.5 mg Oral Granules) } Pack [Trikafta (80 mg / 40 mg / 60 mg; 59.5 mg) Granules]
SCD
Elexacaftor 100 mg / ivacaftor 75 mg / tezacaftor 50 mg Oral Granules
GPCK
{28 (elexacaftor 100 mg / ivacaftor 75 mg / tezacaftor 50 mg Oral Granules) / 28 (ivacaftor 75 mg Oral Granules) } Pack
BPCK
{28 (elexacaftor 100 mg / ivacaftor 75 mg / tezacaftor 50 mg Oral Granules) / 28 (ivacaftor 75 mg Oral Granules) } Pack [Trikafta (100 mg / 50 mg / 75 mg; 75 mg) Granules]
SCDPrescribable
Featured Concept

ivacaftor 150 MG Oral Tablet
(RxCUI 1243046)

Semantic Clinical Drug

Semantic Clinical Drug: The clinical gold standard representing the Generic Name + Strength + Dosage Form.

Mapped Terms
PSNPrescribable
ivacaftor 150 MG Oral Tablet
Prescribable Name
Synonym of another TTY, given for clarity and for display purposes in electronic prescribing applications. Only one PSN per concept.
SCDPrescribable
Featured Concept

ivacaftor 75 MG Oral Granules
(RxCUI 1606868)

Semantic Clinical Drug

Semantic Clinical Drug: The clinical gold standard representing the Generic Name + Strength + Dosage Form.

Mapped Terms
PSNPrescribable
ivacaftor 75 MG Oral Granules
Prescribable Name
Synonym of another TTY, given for clarity and for display purposes in electronic prescribing applications. Only one PSN per concept.
SCDPrescribable
Featured Concept

ivacaftor 75 MG Oral Tablet
(RxCUI 2174388)

Semantic Clinical Drug

Semantic Clinical Drug: The clinical gold standard representing the Generic Name + Strength + Dosage Form.

Mapped Terms
PSNPrescribable
ivacaftor 75 MG Oral Tablet
Prescribable Name
Synonym of another TTY, given for clarity and for display purposes in electronic prescribing applications. Only one PSN per concept.
SCDPrescribable
Featured Concept

elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG Oral Tablet
(RxCUI 2257011)

Semantic Clinical Drug

Semantic Clinical Drug: The clinical gold standard representing the Generic Name + Strength + Dosage Form.

Mapped Terms
PSNPrescribable
elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG Oral Tablet
Prescribable Name
Synonym of another TTY, given for clarity and for display purposes in electronic prescribing applications. Only one PSN per concept.
PSNPrescribable
Featured Concept

elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG Oral Tablet (56) and ivacaftor 150 MG Oral Tablet (28) Pack
(RxCUI 2257012)

Prescribable Name

Prescribable Name: The standardized name preferred by electronic prescribing (eRx) applications for display.

Mapped Terms
GPCKPrescribable
{56 (elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG Oral Tablet) / 28 (ivacaftor 150 MG Oral Tablet) } Pack
Generic Pack
{# (Ingredient + Strength + Dose Form) / # (Ingredient + Strength + Dose Form)} Pack
SYPrescribable
elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG Oral Tablet (56) and ivacaftor 150 MG Oral Tablet (28) Pack
Synonym
Synonym of another TTY, given for clarity.
PSNPrescribable
Featured Concept

trikafta 100 MG / 50 MG / 75 MG and 150 MG Tablet Pack
(RxCUI 2257013)

Prescribable Name

Prescribable Name: The standardized name preferred by electronic prescribing (eRx) applications for display.

Mapped Terms
BPCKPrescribable
{56 (elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG Oral Tablet) / 28 (ivacaftor 150 MG Oral Tablet) } Pack [Trikafta (100 MG / 50 MG / 75 MG; 150 MG)]
Brand Name Pack
{# (Ingredient Strength Dose Form) / # (Ingredient Strength Dose Form)} Pack [Brand Name]
SYPrescribable
trikafta 100 MG / 50 MG / 75 MG and 150 MG Tablet Pack
Synonym
Synonym of another TTY, given for clarity.
SCDPrescribable
Featured Concept

elexacaftor 50 MG / ivacaftor 37.5 MG / tezacaftor 25 MG Oral Tablet
(RxCUI 2557214)

Semantic Clinical Drug

Semantic Clinical Drug: The clinical gold standard representing the Generic Name + Strength + Dosage Form.

Mapped Terms
PSNPrescribable
elexacaftor 50 MG / ivacaftor 37.5 MG / tezacaftor 25 MG Oral Tablet
Prescribable Name
Synonym of another TTY, given for clarity and for display purposes in electronic prescribing applications. Only one PSN per concept.
PSNPrescribable
Featured Concept

elexacaftor 50 MG / ivacaftor 37.5 MG / tezacaftor 25 MG Oral Tablet (56) and ivacaftor 75 MG Oral Tablet (28) Pack
(RxCUI 2557215)

Prescribable Name

Prescribable Name: The standardized name preferred by electronic prescribing (eRx) applications for display.

Mapped Terms
GPCKPrescribable
{56 (elexacaftor 50 MG / ivacaftor 37.5 MG / tezacaftor 25 MG Oral Tablet) / 28 (ivacaftor 75 MG Oral Tablet) } Pack
Generic Pack
{# (Ingredient + Strength + Dose Form) / # (Ingredient + Strength + Dose Form)} Pack
SYPrescribable
elexacaftor 50 MG / ivacaftor 37.5 MG / tezacaftor 25 MG Oral Tablet (56) and ivacaftor 75 MG Oral Tablet (28) Pack
Synonym
Synonym of another TTY, given for clarity.
PSNPrescribable
Featured Concept

trikafta 50 MG / 37.5 MG / 25 MG and 75 MG Pack
(RxCUI 2557216)

Prescribable Name

Prescribable Name: The standardized name preferred by electronic prescribing (eRx) applications for display.

Mapped Terms
BPCKPrescribable
{56 (elexacaftor 50 MG / ivacaftor 37.5 MG / tezacaftor 25 MG Oral Tablet) / 28 (ivacaftor 75 MG Oral Tablet) } Pack [Trikafta (50 MG / 37.5 MG / 25 MG; 75 MG)]
Brand Name Pack
{# (Ingredient Strength Dose Form) / # (Ingredient Strength Dose Form)} Pack [Brand Name]
SYPrescribable
trikafta 50 MG / 37.5 MG / 25 MG and 75 MG Pack
Synonym
Synonym of another TTY, given for clarity.
SCDPrescribable
Featured Concept

elexacaftor 80 MG / ivacaftor 60 MG / tezacaftor 40 MG Oral Granules
(RxCUI 2635013)

Semantic Clinical Drug

Semantic Clinical Drug: The clinical gold standard representing the Generic Name + Strength + Dosage Form.

Mapped Terms
PSNPrescribable
elexacaftor 80 MG / ivacaftor 60 MG / tezacaftor 40 MG Oral Granules
Prescribable Name
Synonym of another TTY, given for clarity and for display purposes in electronic prescribing applications. Only one PSN per concept.
SCDPrescribable
Featured Concept

ivacaftor 59.5 MG Oral Granules
(RxCUI 2635020)

Semantic Clinical Drug

Semantic Clinical Drug: The clinical gold standard representing the Generic Name + Strength + Dosage Form.

Mapped Terms
PSNPrescribable
ivacaftor 59.5 MG Oral Granules
Prescribable Name
Synonym of another TTY, given for clarity and for display purposes in electronic prescribing applications. Only one PSN per concept.
PSNPrescribable
Featured Concept

elexacaftor 80 MG / ivacaftor 60 MG / tezacaftor 40 MG Oral Granules (28) / ivacaftor 59.5 MG Oral Granules (28) Pack
(RxCUI 2635021)

Prescribable Name

Prescribable Name: The standardized name preferred by electronic prescribing (eRx) applications for display.

Mapped Terms
GPCKPrescribable
{28 (elexacaftor 80 MG / ivacaftor 60 MG / tezacaftor 40 MG Oral Granules) / 28 (ivacaftor 59.5 MG Oral Granules) } Pack
Generic Pack
{# (Ingredient + Strength + Dose Form) / # (Ingredient + Strength + Dose Form)} Pack
SYPrescribable
elexacaftor 80 MG / ivacaftor 60 MG / tezacaftor 40 MG Oral Granules (28) / ivacaftor 59.5 MG Oral Granules (28) Pack
Synonym
Synonym of another TTY, given for clarity.
PSNPrescribable
Featured Concept

trikafta 80 MG / 40 MG / 60 MG and 59.5 MG Oral Granules Pack
(RxCUI 2635022)

Prescribable Name

Prescribable Name: The standardized name preferred by electronic prescribing (eRx) applications for display.

Mapped Terms
BPCKPrescribable
{28 (elexacaftor 80 MG / ivacaftor 60 MG / tezacaftor 40 MG Oral Granules) / 28 (ivacaftor 59.5 MG Oral Granules) } Pack [Trikafta (80 MG / 40 MG / 60 MG; 59.5 MG) Granules]
Brand Name Pack
{# (Ingredient Strength Dose Form) / # (Ingredient Strength Dose Form)} Pack [Brand Name]
SYPrescribable
Trikafta 80 MG / 40 MG / 60 MG and 59.5 MG Oral Granules Pack
Synonym
Synonym of another TTY, given for clarity.
SCDPrescribable
Featured Concept

elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG Oral Granules
(RxCUI 2635024)

Semantic Clinical Drug

Semantic Clinical Drug: The clinical gold standard representing the Generic Name + Strength + Dosage Form.

Mapped Terms
PSNPrescribable
elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG Oral Granules
Prescribable Name
Synonym of another TTY, given for clarity and for display purposes in electronic prescribing applications. Only one PSN per concept.
PSNPrescribable
Featured Concept

elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG Oral Granules (28) / ivacaftor 75 MG Oral Granules (28) Pack
(RxCUI 2635025)

Prescribable Name

Prescribable Name: The standardized name preferred by electronic prescribing (eRx) applications for display.

Mapped Terms
GPCKPrescribable
{28 (elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG Oral Granules) / 28 (ivacaftor 75 MG Oral Granules) } Pack
Generic Pack
{# (Ingredient + Strength + Dose Form) / # (Ingredient + Strength + Dose Form)} Pack
SYPrescribable
elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG Oral Granules (28) / ivacaftor 75 MG Oral Granules (28) Pack
Synonym
Synonym of another TTY, given for clarity.
PSNPrescribable
Featured Concept

trikafta 100 MG / 50 MG / 75 MG and 75 MG Oral Granules Pack
(RxCUI 2635026)

Prescribable Name

Prescribable Name: The standardized name preferred by electronic prescribing (eRx) applications for display.

Mapped Terms
BPCKPrescribable
{28 (elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG Oral Granules) / 28 (ivacaftor 75 MG Oral Granules) } Pack [Trikafta (100 MG / 50 MG / 75 MG; 75 MG) Granules]
Brand Name Pack
{# (Ingredient Strength Dose Form) / # (Ingredient Strength Dose Form)} Pack [Brand Name]
SYPrescribable
Trikafta 100 MG / 50 MG / 75 MG and 75 MG Oral Granules Pack
Synonym
Synonym of another TTY, given for clarity.

Understanding RxNorm Mapping for Trikafta

RxNorm is a normalized naming system developed by the National Library of Medicine (NLM) to bridge the gap between different drug terminologies. By mapping NDC 51167-331 to RxCUI 1243046, 1606868, 2174388, 2257011, 2257012, 2257013, 2557214, 2557215, 2557216, 2635013, 2635020, 2635021, 2635022, 2635024, 2635025, 2635026, this page provides the standardized "source of truth" required for hospital systems, e-prescribing software, and pharmacy benefit managers (PBMs) to communicate without errors.

Term Type (TTY) Legend for This Page

The clinical cards above utilize specific Term Types (TTY) to define the granularity of the drug concept:

  • PSN Prescribable Name: The standardized name preferred by electronic prescribing (eRx) applications for display.
  • SCD Semantic Clinical Drug: The clinical gold standard representing the Generic Name + Strength + Dosage Form.
  • GPCK Generic Pack: A standardized concept for a clinical kit containing multiple generic components.
  • SY Synonym: An alternative clinical name or alias provided for search and retrieval clarity.
  • BPCK Branded Pack: A standardized concept for a clinical kit containing multiple branded components.

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