Boxed Warning (Boxed Warning)
Metoclopramide is a drug used to treat gastrointestinal disorders but can cause a serious and irreversible movement disorder called tardive dyskinesia. Patients who experience signs or symptoms of tardive dyskinesia should discontinue treatment with metoclopramide as there is no known cure for the disorder. Prolonged treatment with metoclopramide can increase the risk of tardive dyskinesia, and the drug should be avoided for longer than 12 weeks except in rare cases where it is considered necessary. This information is a warning and should be read thoroughly before starting treatment with metoclopramide.*