Evzio(r) Naloxone Hcl
Product Images NDC 51662-1495

Product Visual Gallery

This gallery contains 13 technical images submitted to the FDA as part of the official labeling for Evzio(r) Naloxone Hcl (NDC 51662-1495). Unlike standard consumer photos, these assets often include clinical data figures, molecular chemical structures, and official manufacturer packaging layouts.

As provided by Hf Acquisition Co Llc, Dba Healthfirst, these visuals offer a comprehensive scientific overview of the product's physical and chemical identity, aiding pharmacists and researchers in product verification and study.

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2nd Inst 1 (2nd Inst 1)

Illustration comparing the EVZIO naloxone injection trainer and the actual EVZIO 2 mg injection. The trainer is shown with a white and black outer case, no needle or medicine, and a reusable red safety guard. The EVZIO 2 mg injection is shown with a blue and purple outer case, contains a needle and medicine, and features a non-reusable red safety guard. The image highlights color differences, usage, and safety features between the trainer and the real product.*

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2nd Inst 2 (2nd Inst 2)

Instructional diagram outlining steps to practice using the Trainer for EVZIO Naloxone HCl. It includes images demonstrating how to pull the Trainer and Red safety guard from the case, position the Trainer against the outer thigh, and reset the Trainer by replacing the Red safety guard and sliding the Trainer back into its case. Notes explain proper handling and voice system reset guidance.*

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Auto Injector Case Label (Auto Injector Case Label)

EVZIO naloxone HCl injection 2mg auto-injector carton label in blue and purple. Includes instructions to pull device from case and a drug viewing window. Highlights use for opioid emergencies and storage instructions. Manufactured for Kaleo and labeled by HF Acquisition Co LLC, DBA HealthFirst.*

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Auto Injector Label (Auto Injector Label)

Evzio naloxone HCl injection 2 mg auto-injector packaging label for opioid emergencies. The label includes illustrated instructions to pull off the red safety guard and place the black end against the patient's outer thigh, pressing firmly for 5 seconds. It advises seeking emergency medical attention and has a drug viewing window with a caution to replace if the solution is discolored, cloudy, or contains particles. The product is manufactured for Kaleo by HF Acquisition Co LLC.*

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Carton Label (Carton Label)

Packaging label for EVZIO(R) NALOXONE HCl 2 mg auto-injector by HF Acquisition Co LLC, DBA HealthFirst. The label indicates the product is for opioid emergencies such as suspected overdose and contains naloxone hydrochloride injection USP 2 mg with sodium chloride and water for injection. The carton includes three units: two Evzio auto-injectors and one trainer. Additional information includes storage instructions, pharmacy patient label area, and contact details.*

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Clinical 1 (Clinical 1)

A data table titled 'Mean Pharmacokinetic Parameters (%CV) for Naloxone Following EVZIO (Naloxone HCl) Intramuscular/Subcutaneous Administration to Healthy Subjects' compares pharmacokinetic parameters across three EVZIO dose groups: 0.4 mg, 0.8 mg (two 0.4 mg), and 2 mg. Parameters include T_max (hours), C_max (ng/mL), AUC_0-t (ng.h/mL), AUC_0-inf (ng.h/mL), and T_1/2 (hours) with median values and variability percentages.*

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Clinical 2 (Clinical 2)

Pharmacokinetic graphs showing naloxone plasma concentration (ng/mL) over time postdose (hours) for EVZIO Naloxone HCl injections at three dosages: 2 mg, 0.8 mg (two 0.4 mg injections), and 0.4 mg. The left graph shows concentration changes up to 6 hours postdose, and the right graph focuses on the first hour postdose, highlighting peak concentrations and early decline patterns for each dose.*

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Inst 1 (Inst 1)

Illustration diagram showing parts of the EVZIO naloxone HCl injection 2 mg auto-injector device and its outer case. Key components labeled include Speaker, LEDs, Base, Safety Guard, and Viewing Windows. The outer case is purple with instructions to pull the device up and visible viewing windows. The device is indicated for opioid emergencies and comes pre-assembled for use.*

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Inst 2 (Inst 2)

Illustrative instructional images for using EVZIO (Naloxone HCl) auto-injector. Step 1 shows removing EVZIO from its outer case with a red safety guard on the device. Step 2 depicts pulling off the red safety guard from the auto-injector, highlighting the black base where the needle is located, with warnings to avoid accidental injection.*

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Inst 3 (Inst 3)

Illustrative instructions for using the EVZIO® Naloxone HCl auto-injector. The steps show placing the black end of EVZIO against the outer thigh through clothing and pressing firmly for 5 seconds, indicated by a stopwatch graphic. Additional guidance includes pinching for infants under 1 year, the device's clicking sound confirming proper use, and advice to seek emergency medical help after injection. The instructions also note that EVZIO cannot be reused and to place the auto-injector back in its case after use without replacing the red safety guard.*

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Inst 4 (Inst 4)

Illustration of a used EVZIO naloxone HCl injection device showing labeled features including the viewing window with red indicator, red LED, base locked status, and needle retracted status. Instructions indicate pulling off the red safety guard and placing the black end against the patient's outer thigh with firm pressure for 5 seconds to administer the injection, accompanied by a click and hiss sound.*

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Serialized Carton Labeling (Serialized Carton Labeling)

EVZIO naloxone HCl injection, USP 2 mg auto-injector carton by HF Acquisition Co LLC, DBA HealthFirst. The carton states use for opioid emergencies such as suspected overdose and includes two Evzio auto-injectors and one trainer. The pack is labeled Rx Only and includes markings for lifting and pressing instructions on top.*

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Structure (Structure)

Chemical structure of naloxone hydrochloride (NALOXONE HCl), showing its molecular framework including hydroxyl groups, a nitrogen-containing ring, and associated hydrochloride.*

* About these descriptions: Image descriptions on this page are generated by automated AI analysis of the product label images from the manufacturer's FDA label submission (SPL). They are provided for reference only and may contain errors or omissions. Always rely on the printed label itself and the official FDA labeling, and consult a pharmacist or healthcare professional with any questions about this product.