Zestoretic Tablet
NDC Package 52427-435-90

View Billable Units, 11-Digit Conversion Format, and RxNorm mappings
Table of Contents
    1. Package Information
    2. Frequently Asked Questions

Package Information

Zestoretic (lisinopril and hydrochlorothiazide) tablets is a medication used to treat high blood pressure. This formulation utilizes a tablet delivery system. Marketed by Almatica Pharma Inc., this product is identified by NDC 52427-435 and is authorized under FDA application NDA019888.

Identification & Billing

NDC Package Code
52427-435-90
Package Description
90 TABLET in 1 BOTTLE
Product Code
52427-435
11-Digit Billing Format
52427043590
Billing Unit
EA - Billing unit of "each" is used when the product is dispensed in discreet units.
Units Per Package
90 EA
RxNorm Crosswalk
  • RxCUI: 197885 - lisinopril 10 MG / hydroCHLOROthiazide 12.5 MG Oral Tablet
  • RxCUI: 197885 - hydrochlorothiazide 12.5 MG / lisinopril 10 MG Oral Tablet
  • RxCUI: 197885 - HCTZ 12.5 MG / lisinopril 10 MG Oral Tablet
  • RxCUI: 197886 - lisinopril 20 MG / hydroCHLOROthiazide 12.5 MG Oral Tablet
  • RxCUI: 197886 - hydrochlorothiazide 12.5 MG / lisinopril 20 MG Oral Tablet

Clinical Specifications

Proprietary Name
Zestoretic
Non-Proprietary Name
Lisinopril And Hydrochlorothiazide
Substance Name
Hydrochlorothiazide; Lisinopril
Dosage Form
Tablet - A solid dosage form containing medicinal substances with or without suitable diluents.
Administration Route
Oral - Administration to or by way of the mouth.
Active Ingredient(s)
Pharmacologic Class
Usage Information
This medication is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains two medications: lisinopril and hydrochlorothiazide. Lisinopril is an ACE inhibitor and works by relaxing blood vessels so that blood can flow more easily. Hydrochlorothiazide is a "water pill" (diuretic) that causes you to make more urine, which helps your body get rid of extra salt and water. This product is used when one drug is not controlling your blood pressure. Your doctor may direct you to take the individual medications first, and then switch you to this combination product. Do not continue taking the individual medications (lisinopril and/or hydrochlorothiazide) after you start this medication.

Regulatory & Marketing

Labeler Name
Almatica Pharma Inc.
Product Type
Human Prescription Drug
FDA Application #
NDA019888
Marketing Category
NDA - A product marketed under an approved New Drug Application.
Start Marketing Date
04-15-2015
Listing Expiration
12-31-2026
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 52427-435-90 identifies a specific commercial package of 90 tablet in 1 bottle of Zestoretic, a human prescription drug labeled by Almatica Pharma Inc.. This product is billed for "EA" each discreet unit and contains an estimated amount of 90 billable units per package. This tablet is formulated for oral use and contains hydrochlorothiazide; lisinopril as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Almatica Pharma Inc. on April 15, 2015. The current certification is valid through December 31, 2026.

What are the primary indications for this medication?

This medication is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains two medications: lisinopril and hydrochlorothiazide. Lisinopril is an ACE inhibitor and works by relaxing blood vessels so that blood can flow more easily. Hydrochlorothiazide is a "water pill" (diuretic) that causes you to make more urine, which helps your body get rid of extra salt and water. This product is used when one drug is not controlling your blood pressure. Your doctor may direct you to take the individual medications first, and then switch you to this combination product. Do not continue taking the individual medications (lisinopril and/or hydrochlorothiazide) after you start this medication.

How is this Almatica Pharma Inc. product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 52427043590. Quantities are measured in per "each", products billed on a per each basis are usually products dispensed in discreet units.. There are 90 total billable units per package. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (5-3-2)
52427-435-90
11-Digit CMS (5-4-2)
52427-0435-90

Note: The zero is added to the Product segment to maintain the 5-4-2 structure.