Active Ingredient
Menthol 10.0%
Activice Spray
FDA Label NDC 53329-996
14 label sections · Submitted to the FDA by Medline Industries, Lp · Indications, Dosage, Usage, and Precautions
Structured Product Label
The following Structured Product Label (SPL) was submitted to the FDA by Medline Industries, Lp for the product Activice (NDC 53329-996). This document serves as the official prescribing information, containing essential scientific data and clinical materials required for healthcare providers and patients.
This specific version of the label includes detailed information regarding active ingredient, purpose, uses, warnings, when using this product, stop use and ask doctor if, if pregnant or breastfeeding,, keep out of reach of children., and other regulatory disclosures. Use the navigation below to review specific sections of the FDA submission.
Label Section Quick Index
Purpose
Topical Analgesic
Uses
For the temporary relief of minor aches and pains of muscles and joints associated with:
- simple backache
- arthritis
- strains
- bruises
- sprains
Warnings
For external use only. Avoid contact with eyes
Flammable: keep away from fire or flame
Do not puncture or incinerate. Contents under pressure.
When Using This Product
- use only as directed
- do not bandage tightly or use with heating pad
- do not apply to wounds or damaged skin
Stop Use And Ask Doctor If
- condition worsens, or if symptoms persist for more than 7 days or clear up and occur again within a few days
- redness is present
- excessive irritation of the skin develops
If Pregnant Or Breastfeeding,
ask a health professional before use.
Keep Out Of Reach Of Children.
If swallowed, get medical help or contact a Poison Control Center right away.
Directions
Adults and children 2 years of age and older:
- spray directly onto affected area without the need to rub, massage or bandage
- repeat if necessary, but do not apply more than 3 to 4 times daily
- wash hands after use.
- do not use, consult a doctor.
Children under 2 years of age:
Other Information
- store at room temperature
Inactive Ingredients
boswellia serrata extract, dimethylsulfone (MSM), eucalyptus oil, glucosamine sulfate, glycerine, PEG-8 dimethicone, pentylene glycol, peppermint oil, SD alcohol 39C, water (USP)
Questions Or Comments?
1-800-MEDLINE (633-5463)
Manufacturing Information
REF: MDSAICESPRY4
Not made with Natural Rubber Latex. Keep product upright. Handle with care. Protect from freezing, avoid excessive heat.
www.medline.com Manufactured in USA for: Medline Industries, LP, Three Lakes Drive, Northfield, IL 60093 USA. 1-800-MEDLINE
*This product is not manufactured or distributed by Reckitt Benckiser Group PLC and/or its subsidiaries, owner of the registered trademark Biofreeze®.
Recent Major Changes
Changes to the indications and usage section on April 2026
* Please review the disclaimer below.
