Promethazine Hydrochloride Tablet
Pricing Report NDC 53746-522-01

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Promethazine Hydrochloride (NDC 53746-522-01) is $0.08146 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Amneal Pharmaceuticals Of New York Llc, this medication is distributed in a 100 TABLET in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.08146
Per EA

Effective Date
Jun 17, 2026
Billable Units
100 EA
Estimated Package Price
$8.15
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
100 TABLET in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Nov 2022, the NADAC wholesale price for (NDC ) has moved within a range of $0.06962 to $0.09946 per EA. Over this 3 years and 7 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.0696 - $0.0995
Market Volatility
42.86% Variance
Latest Trend
4.04%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.08146 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $0.08489 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $0.08635 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $0.08598 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $0.08289 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $0.08241 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $0.08326 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $0.08624 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $0.08799 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $0.08780 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $0.08976 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $0.08922 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $0.08852 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $0.08611 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $0.08793 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $0.08944 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $0.08501 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $0.08054 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2024 $0.07977 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 20, 2024 $0.07797 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 23, 2024 $0.08905 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 18, 2024 $0.08944 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 21, 2024 $0.08259 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 17, 2024 $0.07022 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 19, 2024 $0.07332 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 22, 2024 $0.07008 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 17, 2024 $0.07791 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 20, 2024 $0.08507 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 21, 2024 $0.09522 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 17, 2024 $0.08041 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 20, 2023 $0.09909 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 22, 2023 $0.09063 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 18, 2023 $0.08966 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 20, 2023 $0.08008 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 23, 2023 $0.08724 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 19, 2023 $0.07105 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 21, 2023 $0.08011 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 17, 2023 $0.09946 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 19, 2023 $0.07355 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 22, 2023 $0.09265 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 22, 2023 $0.08292 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 18, 2023 $0.08473 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 21, 2022 $0.07961 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 23, 2022 $0.06962 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 09, 2022 $0.08929 EAC/I - Chain or Independent PharmacyCode 1G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026