Demeclocycline Hydrochloride Tablet
Pricing Report NDC 53746-554-01

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Demeclocycline Hydrochloride (NDC 53746-554-01) is $3.07223 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Amneal Pharmaceuticals Of New York Llc, this medication is distributed in a 100 TABLET in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$3.07223
Per EA

Effective Date
Jun 17, 2026
Billable Units
100 EA
Estimated Package Price
$307.22
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
100 TABLET in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Apr 2024, the NADAC wholesale price for (NDC ) has moved within a range of $2.81256 to $3.96737 per EA. Over this 2 years and 2 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$2.8126 - $3.9674
Market Volatility
41.06% Variance
Latest Trend
5.69%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $3.07223 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $3.25749 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $3.47994 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $3.45419 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $3.22780 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $2.95186 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $2.81256 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $2.87612 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $2.97091 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $3.25012 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $3.50167 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $3.64032 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $3.59452 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $3.53365 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $3.49013 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $3.39824 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $3.26601 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $3.30073 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2024 $3.36013 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 20, 2024 $3.50344 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 23, 2024 $3.45944 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 18, 2024 $3.61483 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 21, 2024 $3.96737 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 17, 2024 $3.83626 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 19, 2024 $3.77535 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 22, 2024 $3.66802 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 17, 2024 $3.88780 EAC/I - Chain or Independent PharmacyCode 1G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026