Demeclocycline Hydrochloride Tablet
Pricing Report NDC 53746-554-01

Current NADAC: $2.51767 per EA · Effective Aug 19, 2026 · Est. package price $251.77 (100 EA)
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

The current wholesale acquisition cost for Demeclocycline Hydrochloride (NDC 53746-554-01) is $2.51767 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Aug 19, 2026.

As a a human prescription drug provided by Amneal Pharmaceuticals Of New York Llc, this medication is distributed in a 100 TABLET in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$2.51767
Per EA

Pricing Unit
Per EA Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Aug 19, 2026
Billable Units
100 EA
Estimated Package Price
$251.77
Data Status
As of Sep 09, 2026
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
G - Generic
Package NDC
53746-554-01
Description
100 TABLET in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Apr 2024, the NADAC wholesale price for (NDC ) has moved within a range of $2.51767 to $3.96737 per EA. Over this 2 years and 4 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$2.5177 - $3.9674
Market Volatility
57.58% Variance
Latest Trend
11.65%

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Aug 19, 2026 $2.51767 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 22, 2026 $2.84960 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 17, 2026 $3.07223 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $3.25749 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $3.47994 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $3.45419 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $3.22780 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $2.95186 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $2.81256 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $2.87612 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $2.97091 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $3.25012 EAC/I - Chain or Independent PharmacyCode 1G - Generic

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: September 09, 2026