Demeclocycline Hydrochloride Tablet
Pricing Report NDC 53746-555-48

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

The current wholesale acquisition cost for Demeclocycline Hydrochloride (NDC 53746-555-48) is $3.47350 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Amneal Pharmaceuticals Of New York Llc, this medication is distributed in a 48 TABLET in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$3.47350
Per EA

Pricing Unit
Per EA Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Jun 17, 2026
Billable Units
48 EA
Estimated Package Price
$166.73
Data Status
As of Jul 08, 2026
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
G - Generic
Package NDC
53746-555-48
Description
48 TABLET in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Apr 2024, the NADAC wholesale price for (NDC ) has moved within a range of $3.47350 to $6.26760 per EA. Over this 2 years and 2 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$3.4735 - $6.2676
Market Volatility
80.44% Variance
Latest Trend
No Change
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $3.47350 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $3.47350 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $3.47350 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $5.99613 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $5.99613 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Oct 22, 2025 $5.61467 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $5.49676 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $5.28312 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $5.29270 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $5.26411 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $5.21295 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $5.15062 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $5.09141 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $4.89142 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $4.78863 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2024 $4.75902 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 20, 2024 $4.76658 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 23, 2024 $4.90872 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 18, 2024 $5.07413 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 21, 2024 $5.18748 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 17, 2024 $5.18748 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 19, 2024 $5.34420 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 22, 2024 $5.84552 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 17, 2024 $6.26760 EAC/I - Chain or Independent PharmacyCode 1G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026