Promethazine Hydrochloride Tablet
Pricing Report NDC 53746-745-01

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Promethazine Hydrochloride (NDC 53746-745-01) is $0.04770 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Amneal Pharmaceuticals Of New York Llc, this medication is distributed in a 100 TABLET in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.04770
Per EA

Effective Date
Jun 17, 2026
Billable Units
100 EA
Estimated Package Price
$4.77
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
100 TABLET in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Oct 2022, the NADAC wholesale price for (NDC ) has moved within a range of $0.03122 to $0.05633 per EA. Over this 3 years and 8 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.0312 - $0.0563
Market Volatility
80.43% Variance
Latest Trend
4.24%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.04770 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $0.04981 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $0.05113 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $0.05383 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $0.05280 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $0.05331 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $0.05130 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $0.05010 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $0.04985 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $0.05089 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $0.05204 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $0.05187 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $0.05306 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $0.05383 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $0.05432 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $0.05286 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $0.04576 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $0.03849 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2024 $0.03798 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 20, 2024 $0.03122 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 23, 2024 $0.04992 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 18, 2024 $0.05633 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 21, 2024 $0.04980 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 17, 2024 $0.03815 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 19, 2024 $0.05067 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 22, 2024 $0.04264 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 17, 2024 $0.04038 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 20, 2024 $0.05371 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 21, 2024 $0.05121 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 17, 2024 $0.05565 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 20, 2023 $0.04588 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 22, 2023 $0.04964 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 18, 2023 $0.04182 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 20, 2023 $0.04521 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 23, 2023 $0.04828 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 19, 2023 $0.04360 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 21, 2023 $0.04861 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 17, 2023 $0.04927 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 19, 2023 $0.04695 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 22, 2023 $0.04747 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 22, 2023 $0.04395 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 18, 2023 $0.04723 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 21, 2022 $0.04673 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 23, 2022 $0.04677 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 19, 2022 $0.05104 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 12, 2022 $0.04672 EAC/I - Chain or Independent PharmacyCode 1G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026