Product Images Clopidogrel Bisulfate

The description is "Clopidogrel 75 mg tablets, prescription only".*

The image shows the impact of Proton Pump Inhibitors (PPIs) on the exposure to Clopidogrel Active Metabolite after taking multiple doses of Clopidogrel 75 mg alone or with PPIs. The graph displays the mean and 90% confidence interval of the effect of different PPIs, including Dexlansoprazole, Lansoprazole, Pantoprazole, and Omeprazole, on the active metabolite AUC compared to taking Clopidogrel alone.*

This is a chart from the CURE Study showing the rates of cardiovascular death, myocardial infarction, and stroke in patients taking a placebo with aspirin versus those taking clopidogrel with aspirin. The chart shows a significantly lower event rate for those taking clopidogrel with aspirin. The study also used other standard therapies as needed.*

This is a figure from the COMMIT study showing the cumulative event rates for death before first discharge. The placebo group had 8.1% deaths and the clopidogrel group had 7.5% deaths. There was a 7% proportional risk reduction with clopidogrel (p=0.03). The x-axis shows the days since randomization up to 28 days, and all treated patients received aspirin.*

The figure 5 shows the cumulative event rates for the combined endpoint of reinfarction, stroke or death, in the COMMIT study. The study included all treated patients who received aspirin. The graph shows that the percentage with death, reinfarction or stroke before the first discharge is 7%, with Placebo: 2310Events (10.1%), and with Clopidogrel: 2121Events (9.2%). The graph also shows that there is a 9% proportional risk reduction (p=0.002) for the Clopidogrel treatment. The X-axis displays the number of days since randomization (up to 28 days).*

This is a description of statistical results from a study investigating the effects of adding Clopidogre to Aspirin on the combined primary endpoint across different subgroups for the COMMIT Study. The results are presented in table format, with percentages, odds ratios, and confidence intervals. There are subgroups based on demographic variables such as sex and age, as well as prognostic index groups based on the absolute risk of primary outcomes. There is also information on the use of fibrinolytic agents. The global Heterogeneity Test result is given.*

The figure shows the effects of adding Clopidogrel to Aspirin in different subgroups in the COMMIT study. The table displays the percentage of events for each subgroup for patients taking Clopidogrel and placebo. The odds ratio and heterogeneity test results are also presented. The subgroups evaluated include Killip class, previous MI, and infarct location. Global heterogeneity test results show a non-significant p-value.*

The text describes a graph (Figure 8) about the cumulative event rate (%) of fatal or non-fatal vascular events in a study called CAPRIE. The graph shows the results over a period of 36 months (3 years) and compares the use of aspirin and clopidogrel. There were 167 vascular events recorded.*