Xyosted Injection
Pricing Report NDC 54436-200-04

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Xyosted (NDC 54436-200-04) is $317.02092 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Antares Pharma, Inc., this medication is distributed in a 4 SYRINGE in 1 CARTON / .5 mL in 1 SYRINGE (54436-200-02) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$317.02092
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
4 SYRINGE in 1 CARTON / .5 mL in 1 SYRINGE (54436-200-02)
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Oct 2019, the NADAC wholesale price for (NDC ) has moved within a range of $238.19583 to $317.20262 per ML. Over this 6 years and 7 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$238.1958 - $317.2026
Market Volatility
33.17% Variance
Latest Trend
0.06%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $317.02092 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 20, 2026 $317.20262 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 01, 2026 $316.92027 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2026 $316.92027 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2026 $316.92027 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 17, 2025 $307.68660 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 19, 2025 $307.63369 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 22, 2025 $307.58278 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 17, 2025 $307.56854 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 20, 2025 $307.58477 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 23, 2025 $307.63798 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 18, 2025 $307.50254 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 21, 2025 $307.24203 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 06, 2025 $308.33893 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 06, 2025 $308.33893 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 06, 2025 $308.33893 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 18, 2024 $299.35818 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 20, 2024 $299.34424 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 23, 2024 $299.48120 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 18, 2024 $299.52039 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 21, 2024 $299.63966 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 17, 2024 $299.71509 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 19, 2024 $299.59844 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 22, 2024 $299.90455 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 04, 2024 $299.14115 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 04, 2024 $299.14115 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 04, 2024 $299.14115 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Oct 18, 2023 $290.42548 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 18, 2023 $290.42548 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 03, 2023 $291.24238 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 03, 2023 $291.24238 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 03, 2023 $291.24238 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jul 01, 2022 $277.37634 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2022 $277.37634 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 01, 2022 $277.37634 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Apr 20, 2022 $264.17045 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Apr 20, 2022 $264.17045 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2021 $262.72653 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2021 $262.72653 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 01, 2021 $262.72653 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Apr 21, 2021 $250.21813 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Apr 21, 2021 $250.21813 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2020 $250.10086 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2020 $250.10086 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 01, 2020 $250.10086 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Oct 23, 2019 $238.19583 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 23, 2019 $238.19583 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Oct 23, 2019 $238.19583 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026