Isotretinoin Capsule
Pricing Report NDC 57664-020-97

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Isotretinoin (NDC 57664-020-97) is $11.93600 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jan 21, 2026.

As a a human prescription drug provided by Sun Pharmaceutical Industries, Inc., this medication is distributed in a 3 BLISTER PACK in 1 BOX / 10 CAPSULE in 1 BLISTER PACK (57664-020-98) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$11.93600
Per EA

Effective Date
Jan 21, 2026
Billable Units
3 EA
Estimated Package Price
$35.81
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
3 BLISTER PACK in 1 BOX / 10 CAPSULE in 1 BLISTER PACK (57664-020-98)
Pricing Methodology Explanation
The NADAC was carried forward from the previous file.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since May 2021, the NADAC wholesale price for (NDC ) has moved within a range of $2.53140 to $24.88400 per EA. Over this 4 years and 8 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$2.5314 - $24.8840
Market Volatility
883.01% Variance
Latest Trend
3.96%
Date Unit Price Unit Source Method Rate
Jan 21, 2026 $11.93600 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 21, 2026 $11.93600 EAC/I - Chain or Independent PharmacyCode 4, 6G - Generic
Dec 17, 2025 $11.48081 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 19, 2025 $11.83338 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 22, 2025 $11.37829 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 17, 2025 $11.31423 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 20, 2025 $10.75156 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 23, 2025 $10.88689 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 18, 2025 $11.12024 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 21, 2025 $11.21941 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 23, 2025 $11.33012 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 19, 2025 $11.73099 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 19, 2025 $12.02249 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 22, 2025 $12.73613 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 18, 2024 $11.90787 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 23, 2024 $11.90787 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 23, 2024 $11.90787 EAC/I - Chain or Independent PharmacyCode 4, 6G - Generic
Jun 19, 2024 $14.07774 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 19, 2024 $14.07774 EAC/I - Chain or Independent PharmacyCode 4, 6G - Generic
May 22, 2024 $15.44584 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 17, 2024 $15.33453 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 24, 2021 $24.88400 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 24, 2021 $24.88400 EAC/I - Chain or Independent PharmacyCode 4, 6G - Generic
Jun 23, 2021 $2.56329 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 19, 2021 $2.53140 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026