Isotretinoin Capsule
Pricing Report NDC 57664-025-97

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Isotretinoin (NDC 57664-025-97) is $5.30671 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Sun Pharmaceutical Industries, Inc., this medication is distributed in a 3 BLISTER PACK in 1 BOX / 10 CAPSULE in 1 BLISTER PACK (57664-025-98) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$5.30671
Per EA

Effective Date
Jun 17, 2026
Billable Units
3 EA
Estimated Package Price
$15.92
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
3 BLISTER PACK in 1 BOX / 10 CAPSULE in 1 BLISTER PACK (57664-025-98)
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since May 2021, the NADAC wholesale price for (NDC ) has moved within a range of $3.04144 to $26.76650 per EA. Over this 5 years period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$3.0414 - $26.7665
Market Volatility
780.06% Variance
Latest Trend
4.06%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $5.30671 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 20, 2026 $5.09986 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 22, 2026 $5.92641 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 18, 2026 $7.19991 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 18, 2026 $9.29408 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 21, 2026 $12.10022 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 17, 2025 $14.43455 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 19, 2025 $15.92486 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 22, 2025 $15.04773 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 17, 2025 $13.93097 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 20, 2025 $12.87776 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 23, 2025 $12.61751 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 18, 2025 $13.01429 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 21, 2025 $13.44085 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 23, 2025 $13.81641 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 19, 2025 $14.49561 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 19, 2025 $15.33684 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 22, 2025 $16.42135 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 18, 2024 $16.85601 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 20, 2024 $16.70926 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 23, 2024 $17.30935 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 18, 2024 $17.60478 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 21, 2024 $18.25920 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 17, 2024 $18.95084 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 19, 2024 $18.30376 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 22, 2024 $19.41042 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Apr 17, 2024 $18.93975 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Mar 20, 2024 $17.70678 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Feb 21, 2024 $17.05752 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jan 17, 2024 $18.44267 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Dec 20, 2023 $17.32093 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Nov 22, 2023 $17.95367 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Oct 18, 2023 $16.72822 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Sep 20, 2023 $14.16467 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Aug 23, 2023 $18.88392 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jul 19, 2023 $15.80564 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 21, 2023 $17.48983 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 22, 2022 $15.18700 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 22, 2022 $15.18700 EAC/I - Chain or Independent PharmacyCode 4, 6G - Generic
Jun 24, 2021 $26.76650 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
Jun 24, 2021 $26.76650 EAC/I - Chain or Independent PharmacyCode 4, 6G - Generic
Jun 23, 2021 $3.04144 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic
May 19, 2021 $3.43635 EAC/I - Chain or Independent PharmacyCode 1, 6G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026