Effexor Capsule, Extended Release
Pricing Report NDC 58151-127-77

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Effexor Xr (NDC 58151-127-77) is $21.59051 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Viatris Specialty Llc, this medication is distributed in a 90 CAPSULE, EXTENDED RELEASE in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$21.59051
Per EA

Effective Date
Jun 17, 2026
Billable Units
90 EA
Estimated Package Price
$1,943.15
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
90 CAPSULE, EXTENDED RELEASE in 1 BOTTLE
Generic Benchmark
The generic equivalent rate is $0.11695 (Effective: Jun 17, 2026)
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Oct 2024, the NADAC wholesale price for (NDC ) has moved within a range of $20.00910 to $21.60939 per EA. Over this 1 year and 8 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$20.0091 - $21.6094
Market Volatility
8.00% Variance
Latest Trend
0.09%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $21.59051 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jun 17, 2026 $21.59051 EAC/I - Chain or Independent PharmacyCode 1B - Brand
May 20, 2026 $21.60939 EAC/I - Chain or Independent PharmacyCode 1B - Brand
May 20, 2026 $21.60939 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jan 01, 2026 $21.60660 EAC/I - Chain or Independent PharmacyCode 2B - Brand
Jan 01, 2026 $21.60660 EAC/I - Chain or Independent PharmacyCode 2B - Brand
Jan 01, 2026 $21.60660 EAC/I - Chain or Independent PharmacyCode 3B - Brand
Jan 01, 2026 $21.60660 EAC/I - Chain or Independent PharmacyCode 4B - Brand
Jan 01, 2026 $21.60660 EAC/I - Chain or Independent PharmacyCode 4B - Brand
Jan 01, 2026 $21.60660 EAC/I - Chain or Independent PharmacyCode 2B - Brand
Jan 01, 2026 $21.60660 EAC/I - Chain or Independent PharmacyCode 2B - Brand
Jan 01, 2026 $21.60660 EAC/I - Chain or Independent PharmacyCode 3B - Brand
Jan 01, 2026 $21.60660 EAC/I - Chain or Independent PharmacyCode 4B - Brand
Jan 01, 2026 $21.60660 EAC/I - Chain or Independent PharmacyCode 4B - Brand
Dec 17, 2025 $20.57771 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Dec 17, 2025 $20.57771 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Nov 19, 2025 $20.58460 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Nov 19, 2025 $20.58460 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Sep 17, 2025 $20.60960 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Sep 17, 2025 $20.60960 EAC/I - Chain or Independent PharmacyCode 2B - Brand
Sep 17, 2025 $20.60960 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Sep 17, 2025 $20.60960 EAC/I - Chain or Independent PharmacyCode 2B - Brand
Sep 03, 2025 $20.64013 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Aug 20, 2025 $20.64013 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jul 23, 2025 $20.65553 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jun 18, 2025 $20.62932 EAC/I - Chain or Independent PharmacyCode 1B - Brand
May 21, 2025 $20.60771 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Jan 07, 2025 $20.60937 EAC/I - Chain or Independent PharmacyCode 2B - Brand
Jan 07, 2025 $20.60937 EAC/I - Chain or Independent PharmacyCode 2B - Brand
Jan 07, 2025 $20.60937 EAC/I - Chain or Independent PharmacyCode 2B - Brand
Jan 07, 2025 $20.60937 EAC/I - Chain or Independent PharmacyCode 3B - Brand
Jan 07, 2025 $20.60937 EAC/I - Chain or Independent PharmacyCode 4B - Brand
Dec 18, 2024 $20.00910 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Nov 20, 2024 $20.01221 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Oct 23, 2024 $20.00998 EAC/I - Chain or Independent PharmacyCode 1B - Brand
Oct 02, 2024 $20.01006 EAC/I - Chain or Independent PharmacyCode 1B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026