Enbrel Solution
Pricing Report NDC 58406-044-04

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Enbrel (NDC 58406-044-04) is $2080.53545 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Immunex Corporation, this medication is distributed in a 4 CARTRIDGE in 1 CARTON / 1 mL in 1 CARTRIDGE (58406-044-01) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$2,080.53545
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
4 CARTRIDGE in 1 CARTON / 1 mL in 1 CARTRIDGE (58406-044-01)
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Mar 2020, the NADAC wholesale price for (NDC ) has moved within a range of $1,354.50464 to $2,083.37417 per ML. Over this 6 years and 2 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$1,354.5046 - $2,083.3742
Market Volatility
53.81% Variance
Latest Trend
0.14%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $2080.53545 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 20, 2026 $2083.37417 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 07, 2026 $2081.58469 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 07, 2026 $2081.58469 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 07, 2026 $2081.58469 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 17, 2025 $1982.46161 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 19, 2025 $1982.05103 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 22, 2025 $1981.80620 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 17, 2025 $1981.80620 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 20, 2025 $1982.06183 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 23, 2025 $1983.00641 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 18, 2025 $1982.23328 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 21, 2025 $1982.21188 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 08, 2025 $1981.73186 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 08, 2025 $1981.73186 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 08, 2025 $1981.73186 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 23, 2024 $1852.08585 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 23, 2024 $1852.08585 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Aug 23, 2024 $1852.08585 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 21, 2024 $1798.14160 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 17, 2024 $1798.21859 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 19, 2024 $1798.82947 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 22, 2024 $1798.01533 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 05, 2024 $1800.86263 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 05, 2024 $1800.86263 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 05, 2024 $1800.86263 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 04, 2023 $1715.10727 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 04, 2023 $1715.10727 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 04, 2023 $1715.10727 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jul 01, 2022 $1596.93414 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2022 $1596.93414 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 01, 2022 $1596.93414 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 26, 2022 $1559.50600 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 26, 2022 $1559.50600 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 26, 2022 $1559.50600 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Nov 17, 2021 $1452.05400 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 17, 2021 $1452.05400 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Nov 17, 2021 $1452.05400 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 22, 2021 $1454.73799 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 22, 2021 $1454.73799 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 22, 2021 $1454.73799 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jul 22, 2020 $1354.50464 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 22, 2020 $1354.50464 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 22, 2020 $1354.50464 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Mar 18, 2020 $1356.17150 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Mar 18, 2020 $1356.17150 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Mar 18, 2020 $1356.17150 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026