Me Naphos Mb Hyo 1 Tablet
Pricing Report NDC 58657-454-01

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Me Naphos Mb Hyo 1 (NDC 58657-454-01) is $4.21492 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Method Pharmaceuticals, this medication is distributed in a 100 TABLET in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$4.21492
Per EA

Effective Date
Jun 17, 2026
Billable Units
100 EA
Estimated Package Price
$421.49
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
100 TABLET in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Sep 2020, the NADAC wholesale price for (NDC ) has moved within a range of $2.56901 to $4.43784 per EA. Over this 5 years and 9 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$2.5690 - $4.4378
Market Volatility
72.75% Variance
Latest Trend
1.36%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $4.21492 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $4.27304 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $4.18266 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $4.00802 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $3.94149 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $4.06334 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $4.30132 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $4.29555 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $4.06049 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $3.84672 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $3.78940 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $3.86549 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $3.95553 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $3.94712 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $3.77419 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $3.66764 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $3.75029 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $3.76326 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2024 $3.75794 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 20, 2024 $3.48860 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 23, 2024 $3.71579 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 18, 2024 $3.94574 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 21, 2024 $4.18692 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 17, 2024 $4.06415 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 19, 2024 $3.24016 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 22, 2024 $3.24512 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 17, 2024 $3.42268 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 17, 2024 $3.58102 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 17, 2024 $3.58102 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Dec 20, 2023 $3.47486 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 22, 2023 $3.55994 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 18, 2023 $4.35599 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 23, 2023 $4.43784 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 23, 2023 $4.43784 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Jun 21, 2023 $4.39315 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 21, 2023 $4.39315 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Mar 22, 2023 $3.63196 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 22, 2023 $3.63196 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Feb 22, 2023 $3.03534 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 18, 2023 $3.36929 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 19, 2022 $3.15443 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 19, 2022 $3.15443 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Aug 17, 2022 $3.23101 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 17, 2022 $3.23101 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Jul 20, 2022 $2.99408 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 18, 2022 $2.56901 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 18, 2022 $2.56901 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Mar 23, 2022 $4.05320 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 23, 2022 $4.05320 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Jan 19, 2022 $3.08815 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 19, 2022 $3.08815 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Dec 22, 2021 $2.82291 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 17, 2021 $3.62595 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 20, 2021 $3.64039 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 22, 2021 $3.75864 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 18, 2021 $3.62749 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 21, 2021 $3.11605 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 23, 2021 $3.55875 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 19, 2021 $3.54321 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 21, 2021 $3.36303 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 17, 2021 $3.75056 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 17, 2021 $3.75056 EAC/I - Chain or Independent PharmacyCode 4G - Generic
Jan 20, 2021 $3.66809 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 23, 2020 $3.49520 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 18, 2020 $3.07413 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 09, 2020 $3.74750 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 09, 2020 $3.74750 EAC/I - Chain or Independent PharmacyCode 4G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026