Methotrexate Tablet
Pricing Report NDC 59651-182-01

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Methotrexate (NDC 59651-182-01) is $0.16347 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Aurobindo Pharma Limited, this medication is distributed in a 100 TABLET in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.16347
Per EA

Effective Date
Jun 17, 2026
Billable Units
100 EA
Estimated Package Price
$16.35
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
100 TABLET in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Aug 2020, the NADAC wholesale price for (NDC ) has moved within a range of $0.15065 to $0.50608 per EA. Over this 5 years and 10 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.1507 - $0.5061
Market Volatility
235.93% Variance
Latest Trend
0.36%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.16347 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $0.16406 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $0.16046 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $0.15848 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $0.16022 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $0.16393 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $0.15807 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $0.15301 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $0.15722 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $0.16449 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $0.16944 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $0.16427 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $0.16376 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $0.16088 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $0.16170 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $0.16106 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $0.15552 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $0.15507 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2024 $0.15834 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 20, 2024 $0.16189 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 23, 2024 $0.17412 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 18, 2024 $0.17536 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 21, 2024 $0.17286 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 17, 2024 $0.15507 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 19, 2024 $0.21295 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 22, 2024 $0.15065 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 17, 2024 $0.15170 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 20, 2024 $0.18457 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 21, 2024 $0.19192 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 17, 2024 $0.18363 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 20, 2023 $0.21257 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 22, 2023 $0.23829 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 18, 2023 $0.22665 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 20, 2023 $0.23874 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 23, 2023 $0.27147 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 19, 2023 $0.25799 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 21, 2023 $0.27424 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 17, 2023 $0.26838 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 19, 2023 $0.27481 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 22, 2023 $0.23874 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 22, 2023 $0.19362 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 18, 2023 $0.19531 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 21, 2022 $0.16465 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 23, 2022 $0.19441 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 19, 2022 $0.18348 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 21, 2022 $0.20998 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 17, 2022 $0.22123 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 20, 2022 $0.23350 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 22, 2022 $0.23868 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 18, 2022 $0.25274 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 20, 2022 $0.23823 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 23, 2022 $0.26817 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 23, 2022 $0.25740 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 19, 2022 $0.30190 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 22, 2021 $0.28270 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 17, 2021 $0.29244 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 20, 2021 $0.32244 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 22, 2021 $0.33567 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 18, 2021 $0.34983 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 21, 2021 $0.31966 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 23, 2021 $0.30443 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 19, 2021 $0.34329 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 21, 2021 $0.47172 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 17, 2021 $0.47850 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 17, 2021 $0.50608 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 20, 2021 $0.47738 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 23, 2020 $0.50579 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 18, 2020 $0.40054 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 21, 2020 $0.40544 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 23, 2020 $0.40358 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 19, 2020 $0.43450 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 12, 2020 $0.40567 EAC/I - Chain or Independent PharmacyCode 1G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026