Estradiol Vaginal Inserts Tablet, Film Coated
Pricing Report NDC 59651-439-08

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

The current wholesale acquisition cost for Estradiol Vaginal Inserts (NDC 59651-439-08) is $5.91237 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jul 22, 2026.

As a a human prescription drug provided by Aurobindo Pharma Limited, this medication is distributed in a 8 APPLICATOR in 1 CARTON / 1 TABLET, FILM COATED in 1 APPLICATOR configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$5.91237
Per EA

Pricing Unit
Per EA Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Jul 22, 2026
Billable Units
8 EA
Estimated Package Price
$47.30
Data Status
As of Aug 05, 2026
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
G - Generic
Package NDC
59651-439-08
Description
8 APPLICATOR in 1 CARTON / 1 TABLET, FILM COATED in 1 APPLICATOR
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since May 2025, the NADAC wholesale price for (NDC ) has moved within a range of $5.91237 to $7.19534 per EA. Over this 1 year and 1 month period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$5.9124 - $7.1953
Market Volatility
21.70% Variance
Latest Trend
2.38%
Date Unit Price Unit Source Method Rate
Jul 22, 2026 $5.91237 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 22, 2026 $5.91237 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 17, 2026 $6.05622 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 17, 2026 $6.05622 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $6.13859 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 20, 2026 $6.13859 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $6.42342 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 22, 2026 $6.42342 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $6.74229 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 18, 2026 $6.74229 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $6.90404 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 18, 2026 $6.90404 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $6.84800 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 21, 2026 $6.84800 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $6.83874 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 17, 2025 $6.83874 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $7.00948 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 19, 2025 $7.00948 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $7.00180 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $7.00180 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $6.89930 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $6.89930 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $6.99079 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $6.99079 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $6.99618 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $6.99618 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $7.11046 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $7.11046 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 28, 2025 $7.19534 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 28, 2025 $7.19534 EAC/I - Chain or Independent PharmacyCode 1G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: August 05, 2026